Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Disorders of the Autonomic Nervous System01:18

Disorders of the Autonomic Nervous System

1.3K
The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's...
1.3K
Autoimmune Disorders01:29

Autoimmune Disorders

1.3K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
1.3K
Autonomic Nervous System01:22

Autonomic Nervous System

11.8K
The autonomic nervous system (ANS) is a critical component of the peripheral nervous system, primarily responsible for regulating involuntary bodily functions and maintaining homeostasis. It functions in tandem with the central nervous system (CNS) to seamlessly coordinate various physiological processes without the need for conscious control.
The ANS comprises two main divisions: the sympathetic and parasympathetic divisions. These divisions function antagonistically to maintain a dynamic...
11.8K
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

1.6K
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
1.6K
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

2.6K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
2.6K
Autonomic Nervous System: Overview01:26

Autonomic Nervous System: Overview

7.1K
The human nervous system is divided into two main parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS is composed of the brain and spinal cord, while the PNS contains nerve cells, clusters of nerve cells, and the sensory receptors that are outside the CNS. The PNS has two types of nerve cells: sensory (afferent) and motor (efferent). Sensory cells send signals to the CNS from receptors, and motor cells carry signals from the CNS to organs, muscles, and...
7.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Test-retest reliability of clinical supine-to-stand tests in patients with postural orthostatic tachycardia syndrome: A cautionary tale.

Heart rhythm·2026
Same author

Cutaneous Phosphorylated Alpha-Synuclein in Lewy Body Dementia.

Annals of clinical and translational neurology·2025
Same author

A wolf in synuclein clothing: Creutzfeldt-Jakob disease disguised as MSA.

Clinical autonomic research : official journal of the Clinical Autonomic Research Society·2025
Same author

Clinical Reasoning: A 66-Year-Old Man With Chronic Orthostatic Hypotension.

Neurology·2025
Same author

Letter to the editor regarding "Chronic autonomic symptom burden in long-COVID: a follow-up cohort study."

Clinical autonomic research : official journal of the Clinical Autonomic Research Society·2025
Same author

Exacerbation of Postural Orthostatic Tachycardia Syndrome With Tirzepatide Prescribed for Weight Loss.

JACC. Case reports·2025
Same journal

Key Considerations in Telestroke Program Management.

Continuum (Minneapolis, Minn.)·2026
Same journal

Neurology's Action Potential: Delivering on the Promise of Brain Health.

Continuum (Minneapolis, Minn.)·2026
Same journal

Erratum.

Continuum (Minneapolis, Minn.)·2026
Same journal

Management of Large Artery Atherosclerosis.

Continuum (Minneapolis, Minn.)·2026
Same journal

Thrombolysis, Thrombectomy, and Antithrombotic Therapy for Acute Ischemic Stroke.

Continuum (Minneapolis, Minn.)·2026
Same journal

Stroke in Children and Younger Adults.

Continuum (Minneapolis, Minn.)·2026
See all related articles

Related Experiment Video

Updated: Dec 29, 2025

Quantitative Autonomic Testing
11:40

Quantitative Autonomic Testing

Published on: July 19, 2011

58.4K

Autoimmune Autonomic Disorders.

Steven Vernino

    Continuum (Minneapolis, Minn.)
    |January 31, 2020
    PubMed
    Summary
    This summary is machine-generated.

    Autoimmune autonomic disorders involve the nervous system and inflammation. Identifying these conditions is crucial for potential immunomodulatory treatment.

    More Related Videos

    Single-cell Analysis of Immunophenotype and Cytokine Production in Peripheral Whole Blood via Mass Cytometry
    12:36

    Single-cell Analysis of Immunophenotype and Cytokine Production in Peripheral Whole Blood via Mass Cytometry

    Published on: June 26, 2018

    9.8K
    Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research
    05:55

    Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research

    Published on: December 1, 2023

    1.2K

    Related Experiment Videos

    Last Updated: Dec 29, 2025

    Quantitative Autonomic Testing
    11:40

    Quantitative Autonomic Testing

    Published on: July 19, 2011

    58.4K
    Single-cell Analysis of Immunophenotype and Cytokine Production in Peripheral Whole Blood via Mass Cytometry
    12:36

    Single-cell Analysis of Immunophenotype and Cytokine Production in Peripheral Whole Blood via Mass Cytometry

    Published on: June 26, 2018

    9.8K
    Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research
    05:55

    Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research

    Published on: December 1, 2023

    1.2K

    Area of Science:

    • Neurology
    • Immunology
    • Autonomic Nervous System

    Background:

    • Autonomic disorders can arise from systemic autoimmune diseases or direct nervous system autoimmunity.
    • The autonomic nervous system plays a key role in regulating immune function.
    • Inflammation and the autonomic nervous system are closely interconnected.

    Purpose of the Study:

    • To provide an overview of autonomic disorders with potential autoimmune causes.
    • To highlight the association between autonomic dysfunction and autoimmune conditions.
    • To discuss the diagnostic and therapeutic challenges in autoimmune autonomic disorders.

    Main Methods:

    • Review of recent evidence on the interplay between autoimmunity and the autonomic nervous system.
    • Analysis of clinical manifestations and immunological findings in autoimmune autonomic disorders.
    • Exploration of antibody-mediated autonomic neuropathies, including autoimmune autonomic ganglionopathy.

    Main Results:

    • Autoimmune autonomic ganglionopathy is a key example of an antibody-mediated autonomic disorder.
    • New insights have emerged regarding the clinical spectrum of autoimmune autonomic ganglionopathy.
    • Ganglionic nicotinic acetylcholine receptor antibodies are significant in diagnosing certain autonomic neuropathies.
    • Autonomic dysfunction is increasingly recognized in various systemic and neurological autoimmune diseases.

    Conclusions:

    • Accurate identification of autoimmune autonomic disorders is essential, though challenging.
    • Effective immunomodulatory treatments may be available for some patients.
    • Further research is needed to fully understand and manage these complex conditions.