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1Institute of Fluid Science, Tohoku University, 2-1-1 Katahira, Sendai, 980-8577, Japan. toshiyuki.hayase.a3@tohoku.ac.jp.
Insights
A new method estimates daily continuous blood pressure (DCBP) using pulse rate and a simple circulatory model. This approach overcomes limitations of existing methods, offering appropriate DCBP estimation for a healthier society.
Area of Science:
- Biomedical Engineering
- Physiology
- Health Informatics
Background:
- Daily continuous blood pressure (DCBP) monitoring is crucial for public health.
- Existing blood pressure measurement methods (cuff-based and cuffless) have limitations for DCBP.
- Current cuffless methods using pulse waveform, pulse transit time, or circulation models are not ideal for DCBP.
Purpose of the Study:
- To develop and validate a novel method for estimating daily continuous blood pressure (DCBP).
- To overcome limitations of existing blood pressure monitoring techniques for continuous, long-term measurement.
- To enable more accessible and practical DCBP monitoring.
Main Methods:
- Implementation of a simple circulatory system model incorporating pulse rate measurement.
- Development of a dynamic system model and an inverse control system model.
- Utilizing a wearable device for 24-hour pulse rate monitoring and sphygmomanometry for parameter calibration and validation.
Main Results:
- The proposed method demonstrated appropriate estimation of DCBP.
- Preliminary experiments showed mean absolute errors of 9.4/6.4 mmHg (4 days) and 7.3/5.9 mmHg (5 subjects).
- The model incorporates pulse rate and six parameters reflecting circulatory dynamics.
Conclusions:
- The developed method provides a viable approach for estimating daily continuous blood pressure (DCBP).
- This technique shows promise for improving blood pressure monitoring and contributing to a healthier society.
- Further validation is warranted, but initial results are encouraging for DCBP estimation.
Abstract:
Availability of daily continuous blood pressure (DCBP) has a strong impact to realization of healthy society. However, existing methods to obtain blood pressure of cuff type and cuff-less types utilizing correlation with pulse waveform, pulse transit time or pulse rate; or computation of circulation model are not suitable to obtain DCBP. Here we implemented a method based on a simple circulatory system model using pulse rate measurement to overcome the limitations, and showed that it provides appropriate estimation of DCBP. The present model consists of a circulatory dynamic system model and an inverse model of a circulatory control system with input of pulse rate and six model parameters representing standard pulse rate, elasticity of systemic arteries, peripheral vascular resistance, and characteristics of resistance and stroke volume control. Validity of the DCBP estimation method was examined by preliminary experiment for one subject in four days and that for four subjects in one day. DCBP estimation was performed with 24-hour pulse rate measurement by a wearable device and sphygmomanometer measurement for parameter determination and verification. Mean absolute errors in systolic/diastolic pressures were appropriate ones for preliminary experiments with 9.4/6.4 mmHg in four days and 7.3/5.9 mmHg in five subjects.
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