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A core outcome set for trials of infant-feeding interventions to prevent childhood obesity
Karen Matvienko-Sikar1, Ciara Griffin2, Colette Kelly3
1School of Public Health, University College Cork, Cork, Ireland. karen.msikar@ucc.ie.
Insights
A standardized core outcome set for infant feeding interventions was developed to prevent childhood obesity. This set ensures consistent measurement and reporting in trials, improving the evaluation of interventions for infant health.
Area of Science:
- Pediatrics
- Public Health
- Nutrition Science
Background:
- Standardizing outcome measurement in infant feeding intervention trials is crucial for evaluating and synthesizing their effects on preventing childhood obesity.
- Current research lacks a unified approach to reporting outcomes, hindering comparative analysis and evidence synthesis.
Purpose of the Study:
- To develop a core outcome set for infant feeding interventions targeting children up to one year old.
- The set aims to standardize outcomes measured in randomized trials focused on preventing childhood obesity.
Main Methods:
- A four-stage development process was employed, including a systematic literature review.
- Stakeholder engagement through meetings and an e-Delphi study with diverse national and international participants (clinicians, researchers, parents, etc.) was integral.
Main Results:
- Twenty-six outcomes were identified and grouped into nine domains: breastfeeding/formula feeding, introduction of solids, parent feeding practices, parent knowledge, practical feeding, food environment, dietary intake, infant behavior perception, and child weight.
- These outcomes form a comprehensive set for evaluating infant feeding interventions.
Conclusions:
- The developed core outcome set represents the minimum standard for measurement and reporting in infant feeding intervention trials.
- This standardization will facilitate more robust examination and synthesis of intervention effects on preventing childhood obesity.
Background:
Standardisation of outcomes measured and reported in trials of infant-feeding interventions to prevent childhood obesity is essential to evaluate and synthesise intervention effects. The aim of this study is to develop an infant-feeding core outcome set for use in randomised trials of infant-feeding interventions, with children ≤1 year old, to prevent childhood obesity.
Methods:
Core outcome set development followed four stages: (1) systematic review of outcomes reported in the extant literature; (2) meeting with national and international stakeholders to discuss and clarify identified outcomes; (3) e-Delphi study with national and international stakeholders to prioritise outcomes; (4) meeting with national and international stakeholders to reach consensus on outcomes. Stakeholders in stages 2-4 were paediatricians, general practitioners, nurses, midwives, non-clinician researchers, parents, dieticians, nutritionists, and childcare providers.
Results:
Twenty-six outcomes were identified for inclusion in the core outcome set. These were grouped in nine outcome domains: 'breastfeeding and formula feeding', 'introduction of solids', 'parent feeding practices and styles', 'parent knowledge and beliefs', 'practical feeding', 'food environment', 'dietary intake', 'perceptions of infant behaviour and preferences', and 'child weight'.
Conclusions:
The core outcome set identified in this study is the minimum that should be measured and reported in trials of infant-feeding interventions to prevent childhood obesity. This standardisation of outcomes will enable more comprehensive examination and synthesis of the effects of infant-feeding interventions to prevent childhood obesity.
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