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A descriptive observational study on clinical and dermoscopic features of benign melanocytic neoplasms
Nitya Sarala Nirmala Malladi1, Siddhi Bhalchandra Chikhalkar1, Uday Khopkar1
1Department of Dermatology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.
Background:
Benign melanocytic neoplasms have nests of melanocytic cells and show characteristic dermoscopic features. Clinical and dermoscopic features have not been studied previously in the Indian population.
Aims:
To study the clinical, epidemiological and dermoscopic patterns of benign melanocytic neoplasms.
Methods:
This was a descriptive, observational, single centre study. In 107 patients with melanocytic neoplasms, 167 lesions were clinically examined and studied under the dermoscope and histopathological examination was done when indicated. The lesions were broadly divided as acquired and congenital. Five main dermoscopic patterns were seen-globular, homogenous, reticular, parallel and streaks. If there were two of these patterns in a particular lesion, it was termed 'mixed pattern'. The presence of three or more patterns was called 'multicomponent pattern'. Various other features were also observed.
Results:
The majority of patients belonged to the third decade with a female preponderance. History of increased UV exposure and family history was significant in acquired nevi. The dermoscopic pattern progressed from predominantly reticular in junctional nevi to predominantly globular in compound nevi and lesser pigment in intradermal nevi, with more vascular structures. The congenital melanocytic nevi showed additional features of comedo- like lesions, milia- like cysts, perifollicular pigmentary changes and increased colour variation. Even though colour variation was observed in both acquired and congenital lesions, no signs of dysplasia were seen on histopathology.
Limitations:
A larger sample size is required, with follow up of lesions. No parallel studies in brown skinned population were found for exact comparison.
Conclusion:
Benign melanocytic proliferations are often neglected in our country. This study will help in understanding the course, clinical features and dermoscopic patterns of various benign melanocytic neoplasms, and will be a step forward towards research in our population. To the best of our knowledge, this is the first study of its kind in India.
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