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Updated: Dec 29, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Synthesis of Functionalized Vinylsilanes via Metal-Free Dehydrogenative Silylation of Enamides
Xi-Hao Chang1, Zi-Lu Wang1, Meng Zhao1
1Department of Chemistry , University of Science and Technology of China , Hefei , Anhui 230026 , P. R. China.
Abstract:
A novel method of metal-free dehydrogenative silylation of enamides has been developed. The desired functionalized vinylsilane products were obtained in moderate to good yield and with high stereoselectivities. This protocol displays good tolerance of various functionalities. Furthermore, the high chemoselectivity of this reaction enables us to introduce different unsaturated C-C moieties to the products. The ease of further derivatization of the products to other useful compounds also demonstrates the highly synthetic utility of the current methodology.
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