Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fungal Group Zygomycota01:29

Fungal Group Zygomycota

893
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
893
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

5.1K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.1K
Fungal Phylum Basidiomycota01:26

Fungal Phylum Basidiomycota

741
Basidiomycota is a diverse phylum of fungi that includes ecologically significant decomposers such as white rot fungi, symbionts like mycorrhizal fungi, plant pathogens such as rusts and smuts, and edible species like Agaricus bisporus (the common button mushroom). These fungi play crucial roles in nutrient cycling, symbiotic relationships, and even human health. Their defining feature is the basidium, a microscopic club-shaped structure responsible for producing basidiospores.Fruiting Bodies...
741
Fungal Phylum Ascomycota01:28

Fungal Phylum Ascomycota

882
Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
882
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

338
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
338
Overview of Fungi01:29

Overview of Fungi

1.4K
Fungi are a diverse group of eukaryotes more closely related to animals than other eukaryotes. Fungal cell walls comprise chitin, a polysaccharide that provides structural strength, and glucans, which contribute to flexibility and integrity. Other polysaccharides, such as mannans and galactosans, may supplement or replace chitin in some fungi. These adaptations, along with their preference for acidic environments and tolerance for high osmotic pressure, enable fungi to thrive in various...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Improved Clinical Outcomes with Appropriate Meropenem De-escalation in Patients with Febrile Neutropenia.

Journal of global infectious diseases·2025
Same author

Hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP) in Canada: treatment update and the role of new IV antimicrobials.

Expert review of anti-infective therapy·2023
Same author

Special Issue "Diagnosis and Treatment of Invasive Pulmonary Fungal Infections".

Journal of fungi (Basel, Switzerland)·2023
Same author

Part 2: mucormycosis: focus on therapy.

Expert review of anti-infective therapy·2023
Same author

Part 1: Mucormycosis: prevalence, risk factors, clinical features, and diagnosis.

Expert review of anti-infective therapy·2023
Same author

Streptococcus pneumoniae serotyping and antimicrobial susceptibility: assessment for vaccine efficacy in Canada after the introduction of PCV13.

The Journal of antimicrobial chemotherapy·2023
Same journal

Monographic Issue on New Concepts in Acute Exacerbations of COPD.

Seminars in respiratory and critical care medicine·2026
Same journal

Bidirectional Clinical Interactions among Exacerbations and Comorbidities in COPD: A Narrative Review.

Seminars in respiratory and critical care medicine·2026
Same journal

Radiological Approach to Severe Respiratory Infections and Pulmonary Complications in Immunocompromised Patients.

Seminars in respiratory and critical care medicine·2026
Same journal

Two Sides of the Same Smoke: Decoding Respiratory Bronchiolitis-Associated Interstitial Lung Disease and Alveolar Macrophage Pneumonia.

Seminars in respiratory and critical care medicine·2026
Same journal

Role of Vaccination in the Prevention of ECOPD.

Seminars in respiratory and critical care medicine·2026
Same journal

Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Pharmacological Treatment of AECOPD New Perspectives.

Seminars in respiratory and critical care medicine·2026
See all related articles

Related Experiment Video

Updated: Dec 29, 2025

Sexual Crosses with the Mucoromycete Phycomyces blakesleeanus
05:34

Sexual Crosses with the Mucoromycete Phycomyces blakesleeanus

Published on: June 6, 2025

456

Mucormycosis.

Gail Reid1, Joseph P Lynch2, Michael C Fishbein3

  • 1Division of Infectious Diseases, Department of Medicine, Loyola University Medical Center and Stritch School of Medicine, Maywood, Illinois.

Seminars in Respiratory and Critical Care Medicine
|January 31, 2020
PubMed
Summary
This summary is machine-generated.

Mucormycosis is a severe fungal infection caused by Mucorales molds, particularly affecting immunocompromised individuals and diabetics. Early diagnosis and treatment, including antifungals and surgery, are crucial for improving high mortality rates.

More Related Videos

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice
08:02

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice

Published on: February 18, 2015

10.3K
Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung
15:01

Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung

Published on: September 18, 2021

3.7K

Related Experiment Videos

Last Updated: Dec 29, 2025

Sexual Crosses with the Mucoromycete Phycomyces blakesleeanus
05:34

Sexual Crosses with the Mucoromycete Phycomyces blakesleeanus

Published on: June 6, 2025

456
Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice
08:02

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice

Published on: February 18, 2015

10.3K
Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung
15:01

Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung

Published on: September 18, 2021

3.7K

Area of Science:

  • Mycology
  • Infectious Diseases
  • Immunology

Background:

  • Mucormycosis is a life-threatening infection caused by Mucorales molds.
  • It primarily affects severely immunocompromised individuals in developed countries, and individuals with uncontrolled diabetes in developing countries.
  • The infection has a high mortality rate, especially when disseminated.

Purpose of the Study:

  • To review the epidemiology, clinical presentation, diagnosis, and treatment of mucormycosis.
  • To highlight the importance of early diagnosis and intervention.
  • To discuss current therapeutic strategies and the need for further research.

Main Methods:

  • Histopathology and culture are key diagnostic tools.
  • Polymerase chain reaction (PCR) aids in genus identification.
  • Clinical presentation varies based on host factors and anatomic site.

Main Results:

  • Mucormycosis invades blood vessels, causing thrombosis and tissue necrosis.
  • Rhino-orbital-cerebral mucormycosis is common in diabetics, while pulmonary and disseminated forms are more frequent in transplant recipients and those with hematological malignancies.
  • Delayed treatment significantly worsens outcomes.

Conclusions:

  • Lipid formulations of amphotericin B are the primary treatment.
  • Posaconazole and isavuconazole may be alternatives for refractory or intolerant patients.
  • Early surgical debridement is an important adjunctive therapy, and further studies are needed to optimize treatment duration and roles of different antifungals.