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Primary anorectal malignant melanoma: A case report.
Xingdong Xu1, Ting Ge2, Gang Wang1
1Department of General Surgery.
Medicine
|February 1, 2020
Summary
Anorectal malignant melanoma (AMM) is rare and hard to diagnose. This case study shows successful abdominoperineal resection (APR) for AMM, highlighting the need for better diagnostic and treatment strategies.
Area of Science:
- Oncology
- Surgical Oncology
- Gastroenterology
Background:
- Anorectal malignant melanoma (AMM) is a rare, aggressive cancer with no established treatment consensus.
- Standard treatment, abdominoperineal resection (APR), offers local control but risks complications.
- Wide local excision (WLE) provides faster recovery and preserves bowel function.
Observation:
- A 66-year-old male presented with a two-month history of painless rectal bleeding.
- Colonoscopy and MRI suggested colorectal cancer; immunohistochemistry confirmed malignant melanoma (HMB-45+, S-100+, CD117±, PCK-, ki-67+).
Findings:
- The patient underwent abdominoperineal resection (APR) without adjuvant therapy.
- At 24 months post-operation, the patient shows no signs of recurrence and is in good health.
Implications:
- AMM is frequently misdiagnosed due to its rarity.
- Optimal diagnostic and therapeutic strategies for AMM require further definition.
- Prompt diagnosis and standardized treatment are crucial for improving patient outcomes in AMM.
