An experimental mouse model of Yersinia-induced reactive arthritis
Related Experiment Videos
1Department of Medicine, University of California Los Angeles 90024.
Microbial Pathogenesis
|April 1, 1988
Abstract:
An experimental animal model of Yersinia-induced arthritis was successfully developed in mice using Yersinia enterocolitica WA. In order for the Yersinia to induce arthritis the strain had to be cured of plasmid. The arthritis-susceptible mouse strains were DBA/2 and BDF1. C57B1/6, Balb/c, CBA and DBA/1 were arthritis-resistant. Both the dose of bacteria and the route of administration were critical.