Microfluidic opportunities in printed electrolyte-gated transistor biosensors.
Kevin D Dorfman1, Demetra Z Adrahtas1, Mathew S Thomas1
1Department of Chemical Engineering and Materials Science, University of Minnesota-Twin Cities, 421 Washington Ave. SE, Minneapolis, Minnesota 55455, USA.
Biomicrofluidics
|February 1, 2020
Summary
Printed electrolyte-gated transistors (EGTs) offer a novel biosensing platform. Microfluidics can further enhance EGTs for improved sensitivity and multiplexed detection in diagnostics.
Area of Science:
- Materials Science
- Electrical Engineering
- Biomedical Engineering
Background:
- Printed electrolyte-gated transistors (EGTs) combine printed electronics fabrication with low-voltage ion gel dielectrics.
- EGTs offer label-free, nonoptical sensing with high gain, addressing limitations of conventional chemical field-effect transistors.
- These sensors are suitable for challenging sensing operations.
Purpose of the Study:
- To provide an overview of EGT device fabrication and operation.
- To highlight microfluidic enhancements for EGT sensor performance.
- To explore multiplexing, sample preconcentration, and improved transport for EGTs.
Main Methods:
- Overview of printed electrolyte-gated transistor fabrication processes.
- Discussion of EGT device operation principles.
- Exploration of microfluidic integration techniques for biosensing.
Main Results:
- EGTs demonstrate facile fabrication and low-voltage operation.
- Label-free, nonoptical sensing with high gain is achievable.
- Microfluidic strategies can significantly enhance EGT performance.
Conclusions:
- EGTs represent a promising biosensor platform.
- Microfluidic integration offers significant opportunities for advancing EGT sensor capabilities.
- Further development can lead to improved diagnostic tools.
