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Updated: Dec 29, 2025

Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter
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Left Septal Fascicular Block Following Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy

Enes Elvin Gul1, Andrés Ricardo Pérez-Riera2, Sohaib Haseeb3

  • 1Division of Cardiac Electrophysiology, Madinah Cardiac Centre, Madinah, Saudi Arabia.

Journal of Atrial Fibrillation
|February 1, 2020
PubMed

Insights

Left septal fascicular block, a sign of coronary artery obstruction, can transiently occur after alcohol septal ablation for hypertrophic obstructive cardiomyopathy. This finding highlights potential cardiac electrical complications following the procedure.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Interventional Cardiology

Background:

  • Left septal fascicular block (LSFB) typically indicates critical proximal left anterior descending coronary artery obstruction.
  • Alcohol septal ablation is a treatment for hypertrophic obstructive cardiomyopathy (HOCM).

Observation:

  • A 68-year-old male patient with HOCM underwent alcohol septal ablation.
  • The patient developed a transient left septal fascicular block post-procedure.

Findings:

  • The transient LSFB observed in this case was not associated with coronary artery obstruction.
  • This suggests that iatrogenic causes, such as alcohol septal ablation, can induce LSFB.

Implications:

  • Clinicians should consider iatrogenic causes for LSFB, especially after procedures like alcohol septal ablation.
  • This case expands the differential diagnosis of LSFB beyond coronary artery disease.

Keywords:
alcohol septal ablationhypertrophic cardiomyopathyleft septal fascicular block

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