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Published on: May 10, 2021
Aortic valve neocuspidization in patients under 65 years old
Yasunori Iida1,2, Shigeharu Sawa3, Susumu Fujii3
1Department of Cardiovascular Surgery, Saiseikai Yokohamashi Tobu Hospital, 3-6-1 Shimosueyoshi, Tsurumi-ku, Yokohama, 230-8765, Japan. hhttss1130@gmail.com.
Aortic valve neocuspidization (AVNeo) shows promising early and midterm surgical outcomes in patients under 65. Long-term results and reliability require further verification for this younger patient group.
Area of Science:
- Cardiovascular Surgery
- Cardiac Valve Repair
- Aortic Valve Disease
Background:
- Aortic valve neocuspidization (AVNeo) is an alternative surgical technique for aortic valve disease.
- Outcomes in younger patients (<65 years) undergoing AVNeo require specific evaluation.
Purpose of the Study:
- To assess the surgical outcomes of aortic valve neocuspidization (AVNeo) in patients under 65 years old.
- To evaluate early and midterm results in this specific demographic.
Main Methods:
- AVNeo was performed on 168 patients from December 2010 to February 2019; 36 patients were under 65.
- The cohort included patients with aortic regurgitation (AR) and aortic stenosis (AS).
- Concomitant procedures included coronary artery bypass grafting, mitral valve procedures, and ascending aorta replacement.
Main Results:
- No conversions to valve replacement were necessary; two in-hospital deaths occurred in emergent cases.
- Postoperative gradients significantly decreased in the AS group, and AR was resolved or trivial in most AR patients.
- Freedom from reoperation rates were 100% at 36 months and 93% at 60 months.
Conclusions:
- AVNeo demonstrates suitability for patients under 65 based on early and midterm outcomes.
- Further long-term follow-up is essential to confirm the durability and reliability of AVNeo in this population.
Related Concept Videos
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aortic Regurgitation I: Introduction
Aortic Regurgitation III: Medical Management
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Mitral Stenosis I: Introduction
Mitral Stenosis III: Medical Management

