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Published on: May 26, 2023
Utility of percutaneous thrombin injection for treating visceral pseudoaneurysms
Ujjwal Gorsi1, Vivek Agarwal1, Mohamed Yaser1
1Department of Radiodiagnosis, PGIMER, Chandigarh, India.
Percutaneous thrombin injection shows promise for treating visceral arterial pseudoaneurysms (PAs). This minimally invasive technique achieved technical success in 10/19 patients, particularly for smaller distal PAs, with no complications.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Gastroenterology
Background:
- Visceral arterial pseudoaneurysms (PAs) are rare but serious vascular abnormalities.
- Causes include pancreatitis, iatrogenic injury, infection, and trauma.
- Treatment options for PAs have evolved, with a need for minimally invasive approaches.
Purpose of the Study:
- To evaluate the efficacy and outcomes of percutaneous thrombin injection for visceral arterial pseudoaneurysms (PAs).
- To assess the safety and technical success of this novel treatment modality.
Main Methods:
- Retrospective review of 19 patients with visceral PAs treated between 2014-2019.
- Percutaneous ultrasound-guided thrombin injection was the primary intervention.
- Technical success was defined by the absence of PA flow on follow-up ultrasonography.
Main Results:
- Overall technical success rate was 10/19 patients.
- Higher success rates were observed in distal branch PAs (9/13) compared to main vessel PAs (1/6).
- Smaller pseudoaneurysms (<23mm) had better outcomes (7/12) than larger ones (3/7); no complications were reported.
Conclusions:
- Ultrasound-guided percutaneous thrombin injection offers a painless, cost-effective, and radiation-free treatment for visceral pseudoaneurysms.
- This technique demonstrates potential as a novel therapeutic option.
- Further large-scale studies are warranted to confirm its efficacy.
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