Fungal infection in a post-renal transplant patient with Diaporthe

K Vichitra1, Lokeshwari Gopal1, Balajee Govindarao2

  • 1Department of Microbiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.

Insights

Fungal infections after kidney transplants are common. This report details a rare case of Diaporthe infection in a renal transplant patient, successfully treated with itraconazole.

Area of Science:

  • Mycology
  • Transplant Infectious Diseases

Background:

  • Post-renal transplant fungal infections pose significant mortality and morbidity risks.
  • Commonly identified fungi include Candida, Cryptococcus, and Aspergillus species.

Observation:

  • A renal transplant recipient with hypothyroidism and a pacemaker developed an infection caused by Diaporthe.
  • Diaporthe is an endophytic fungus typically associated with plants, rarely reported in humans.

Findings:

  • The patient, on immunosuppressants, was diagnosed with Diaporthe infection.
  • Successful treatment was achieved using itraconazole at a dosage of 200 mg.

Implications:

  • This case highlights Diaporthe as a potential opportunistic pathogen in immunocompromised individuals.
  • It underscores the importance of considering rare fungal species in transplant recipients with unusual infections.

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