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Asthma: Pathogenesis and Management01:20

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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Occupational asthma.

M Cormier1, C Lemière1

  • 1Centre intégré universitaire de santé et de services sociaux du Nord-de-l'Île-de-Montréal, Hôpital du Sacré Cœur de Montréal, Université de Montréal, Montréal, QC, Canada.

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
|February 2, 2020
PubMed
Summary
This summary is machine-generated.

Occupational asthma (OA), including sensitiser-induced and irritant-induced asthma (IIA), is common and costly. Early diagnosis and management are crucial, though many patients experience persistent symptoms.

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Area of Science:

  • Pulmonology and Occupational Medicine

Background:

  • Work-related asthma (occupational asthma, OA) is a significant global health and economic issue.
  • OA encompasses sensitiser-induced asthma and irritant-induced asthma (IIA), presenting diagnostic challenges due to non-specific symptoms and underdiagnosis.

Purpose of the Study:

  • To provide a comprehensive overview of the epidemiology, clinical features, diagnosis, and management of occupational asthma.
  • To highlight the importance of early and accurate diagnosis for effective patient management and to prevent unnecessary occupational displacement.

Main Methods:

  • Review of existing literature on occupational asthma, covering its various forms and clinical aspects.
  • Exploration of diagnostic challenges and the necessity of comprehensive testing for confirmed cases.

Main Results:

  • Occupational asthma is prevalent and poses a substantial burden, yet it is frequently underdiagnosed.
  • Sensitiser-induced OA results from workplace sensitization, while IIA can occur after acute intense or chronic low-level irritant exposure.
  • Up to 70% of OA patients may have persistent asthma even after optimal management.

Conclusions:

  • Early and accurate diagnosis of occupational asthma is critical for appropriate management and to guide exposure-related decisions.
  • Despite interventions, persistent asthma remains a common outcome for many individuals diagnosed with OA.