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Depression and anxiety in hospitalized patients on contact precautions for multidrug-resistant microorganisms
Eline Maria Granzotto1, Aline Maciel Gouveia1, Juliano Gasparetto1
1School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba PR, Brazil.
Background:
Contact precautions for patients with multidrug-resistant organisms (MDROs) have been associated with adverse effects. The aim of this study was, therefore, to evaluate the level of anxiety and depression through different standardized scales in patients isolated by MDROs.
Methods:
This is a case-control study with hospitalized patients on contact precautions for MDROs. A questionnaire survey was conducted to analyse the presence and level of depression and anxiety. A multivariable analysis was performed to define independent questions for anxiety/depression scores to create a short questionnaire facilitating a practical approach to the care of hospitalized patients with MDROs. A receiver operating characteristic (ROC) curve was plotted to determine the diagnostic ability of the simplified score.
Results:
A total of 141 patients were included in the study, among whom 68 were isolated because of MDRO colonization while 73 were not isolated (control-group). Forty-five (31.9%) patients had some degree of anxiety. Patients in MDRO contact isolation had a higher level of anxiety than those who were not isolated (55.9% vs. 9.6%, p < 0.001). The equation obtained by multivariated analysis allowed for the construction of a score with ROC area of 0.949 and a sensitivity of 91.1%.
Conclusion:
Contact isolation for MDROs is associated with increased depression and anxiety. A simple anxiety score was developed and should be validated for screening.
Insights
Patients isolated due to multidrug-resistant organisms (MDROs) experience significantly higher anxiety and depression. This study developed a simple anxiety score to help screen patients in contact isolation.
Area of Science:
- Infectious Diseases
- Psychiatry
- Hospital Epidemiology
Background:
- Contact precautions for multidrug-resistant organisms (MDROs) are linked to negative patient outcomes.
- Understanding the psychological impact of isolation is crucial for patient care.
Purpose of the Study:
- To assess anxiety and depression levels in patients isolated for MDROs.
- To develop a practical screening tool for anxiety in these patients.
Main Methods:
- A case-control study involving 141 hospitalized patients.
- Questionnaire surveys and multivariable analysis were used to evaluate anxiety and depression.
- A simplified anxiety score was developed and validated using ROC curve analysis.
Main Results:
- Patients in MDRO contact isolation showed significantly higher anxiety (55.9%) compared to controls (9.6%).
- A multivariable analysis yielded an equation for a simplified anxiety score.
- The developed score demonstrated high diagnostic ability with an ROC area of 0.949 and 91.1% sensitivity.
Conclusions:
- Contact isolation for MDROs is associated with increased psychological distress, specifically anxiety and depression.
- A validated, simplified anxiety score can aid in the practical screening and management of isolated patients.
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