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Related Experiment Video

Updated: Dec 29, 2025

Three-dimensional Printing of Thermoplastic Materials to Create Automated Syringe Pumps with Feedback Control for Microfluidic Applications

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Published on: August 30, 2018

Open-source, 3D-printed Peristaltic Pumps for Small Volume Point-of-Care Liquid Handling.

Michael R Behrens¹, Haley C Fuller¹, Emily R Swist¹

¹Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States.

Scientific Reports

|February 2, 2020

Summary

A low-cost, open-source peristaltic pump was developed for microfluidic point-of-care diagnostics. This 3D-printed device offers precise liquid handling for broader healthcare applications.

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Last Updated: Dec 29, 2025

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Area of Science:

Biomedical Engineering
Microfluidics
Diagnostic Technology

Background:

Microfluidic devices are valuable point-of-care diagnostic tools.
External liquid handling equipment increases cost and complexity, limiting adoption in low-resource settings.

Purpose of the Study:

To develop a low-cost, open-source peristaltic pump for microfluidic applications.
To enable wider adoption of microfluidic diagnostics in resource-limited environments.

Main Methods:

Constructed a peristaltic pump using 3D-printed parts and common hardware.
Integrated an Arduino microcontroller for programmable flow control.
Utilized silicone rubber tubing (1.5-3 mm diameter).

Main Results:

Achieved a low system cost of approximately $120.
Demonstrated flow rates up to 1.6 mL/min.
Enabled custom flow profiles for various microfluidic tasks.

Conclusions:

The developed pump is a cost-effective solution for microfluidic liquid handling.
This open-source device can enhance the accessibility of point-of-care diagnostics.
The pump supports diverse applications, including cellular mechanobiology studies.