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Natural Products and Their Therapeutic Effect on Autism Spectrum Disorder
Satarupa Deb1, Banashree Chetia Phukan1, Ankumoni Dutta1
1Cellular and Molecular Neurobiology Laboratory, Department of Life Science and Bioinformatics, Assam University, Silchar, Assam, India.
Autism Spectrum Disorder (ASD) involves social interaction challenges and repetitive behaviors. Research is exploring promising plant-based natural products as potential therapeutic interventions for autism.
Area of Science:
- Neuroscience
- Developmental Biology
- Pharmacology
Background:
- Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder impacting social interaction and behavior.
- Neuroanatomical studies reveal altered brain development in individuals with ASD.
- Current treatments have limitations and adverse side effects, prompting research into alternatives.
Purpose of the Study:
- To review major plant-based natural products with potential therapeutic benefits for ASD.
- To explore the efficacy and mechanisms of natural compounds in managing ASD symptoms.
Main Methods:
- Literature review of scientific studies on herbal remedies and autism.
- Analysis of neuroanatomical and cellular processes implicated in ASD.
- Examination of clinical trials investigating natural compounds for autism.
Main Results:
- Several plant-derived natural products show promise in preclinical and clinical studies.
- These natural compounds may address atypical neurogenesis, neuronal migration, and maturation.
- Evidence suggests potential for ameliorating behavioral deficits associated with ASD.
Conclusions:
- Herbal remedies offer a promising avenue for developing novel therapeutic interventions for ASD.
- Further research is needed to confirm efficacy and understand the mechanisms of action.
- Natural compounds may provide safer alternatives or complementary treatments for autism.
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