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Updated: Dec 29, 2025

Formation of Dispersible Taohong Siwu Tablets
Published on: February 3, 2023
Mechanical strength, structural and hydration properties of ethanol-treated starch tablets and their impact on the
Achmat Sarifudin1, Siriwat Soontaranon2, Jomjai Peerapattana3
1School of Food Technology, Institute of Agricultural Technology, Suranaree University of Technology, Muang, Nakhon Ratchasima 30000, Thailand; Research Center for Appropriate Technology, Indonesian Institute of Sciences (P2TTG-LIPI), Jl. K.S. Tubun No. 5, Subang 41213, West Java, Indonesia.
Abstract:
Ethanol-treated starch (ETS) shows potentiality to be used for binder of pharmaceutical tablets. This study was aimed to evaluate the mechanical strength, structural and hydration properties of ETS tablets and ETS tablets containing lauric acid and ascorbic acid and their release behavior. ETS was prepared from cassava starch at the temperatures of 80, 90, and 100 °C. The active compounds were entrapped within the ETS tablets by two methods, including dry mixing and ethanol solubilisation. The results indicated that ETS tablets from temperatures of 80 °C showed granular shapes, had high friability and low crushing strength indexes, and dispersed and released active ingredients rapidly upon contact with water. Meanwhile, ETS tablets from temperatures of 90 and 100 °C exhibited non-granular particles, had low friability and high crushing strength indexes. Upon hydration, the tablets of non-granular ETS containing lauric acid eroded gradually and released active ingredients during tablet's erosion, meanwhile ascorbic acid diffused out gradually from the swelled tablets.
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