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Clinical study designs and patient selection methods based on genomic biomarkers: Points-to-consider documents

Masahiro Tohkin1, Yoshiro Saito2, Satomi Yagi3

  • 1Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan.

Drug Metabolism and Pharmacokinetics
|February 3, 2020
PubMed
Summary

Genomic biomarkers enhance precision medicine and drug development by predicting treatment outcomes. This paper compiles guidelines for applying genomic biomarkers in clinical trials to advance molecularly targeted therapies.

Keywords:
Clinical trialGenomic biomarkerPatient selectionPrecision medicineStudy design

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