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Related Concept Videos

Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

199
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
199
ECG Interpretation of Arrhythmias I: Sinus Arrhythmias01:16

ECG Interpretation of Arrhythmias I: Sinus Arrhythmias

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Arrhythmias are disturbances in the heart's rhythm that lead to abnormal heartbeats. These irregularities can originate from different parts of the heart and are classified based on their origin and nature.
Types of Arrhythmias
Sinus Node Arrhythmias
Sinus Bradycardia: Originating from the sinoatrial (SA) node, sinus bradycardia involves slower impulses, resulting in a heart rate of less than 60 beats per minute (bpm). Causes include sleep, vagal stimulation, beta-blockers, hypothyroidism,...
663
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

308
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
308
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

374
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
374
Pericarditis I: Introduction01:22

Pericarditis I: Introduction

238
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
238
Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

230
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
230

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Related Experiment Video

Updated: Dec 29, 2025

Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice
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Lyme carditis presenting as sick sinus syndrome.

Naomi Gazendam1, Cynthia Yeung1, Adrian Baranchuk1

  • 1Department of Medicine, Queen's University, Kingston, Canada.

Journal of Electrocardiology
|February 3, 2020
PubMed
Summary

Lyme carditis, a heart complication of Lyme disease, can cause severe sinus pauses. Prompt antibiotic treatment resolved these cardiac conduction abnormalities in a young male patient.

Keywords:
Lyme carditisLyme diseaseSick sinus syndromeSinus pauses

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Area of Science:

  • Infectious Diseases
  • Cardiology
  • Neurology

Background:

  • Lyme disease, caused by Borrelia burgdorferi, is a tickborne illness.
  • Lyme carditis, a cardiac manifestation, can lead to atrioventricular block or sick sinus syndrome.
  • Cardiac involvement in Lyme disease requires prompt diagnosis and management.

Observation:

  • A previously healthy 22-year-old male presented with syncope.
  • A 2-week Holter monitor revealed prolonged sinus pauses (6.5 and 6.8 seconds).
  • Positive Lyme serology, confirmed by Western blot, indicated infection.

Findings:

  • The patient received 8 days of intravenous antibiotics for Lyme carditis.
  • A subsequent stress test showed no conduction abnormalities.
  • Complete resolution of sinus pauses was observed post-treatment.

Implications:

  • Early diagnosis and treatment of Lyme carditis are crucial for cardiac recovery.
  • Intravenous and oral antibiotic regimens effectively manage Lyme carditis-related conduction abnormalities.
  • This case highlights the importance of considering Lyme disease in young adults presenting with syncope and cardiac conduction issues.