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Granulomatous lobular mastitis: Clinical update and case study.

Meagan E Brennan¹, Melissa Morgan², Ghaith Bahjat Heilat³

¹FRACGP, FASBP, PhD, Senior Staff Specialist, Westmead Breast Cancer Institute, Westmead Hospital, NSW; Clinical Academic, School of Medicine Sydney, University of Notre Dame Australia, NSW; Clinical Associate Professor, Northern and Westmead Clinical Schools, School of Medicine, Faculty of Medicine and Health, University of Sydney, NSW.

Australian Journal of General Practice

|February 3, 2020

Summary

Granulomatous lobular mastitis (GM) is a rare inflammatory breast condition that can mimic cancer. Early diagnosis and supportive care are crucial for managing this challenging condition.

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Area of Science:

Breast pathology
Inflammatory conditions
Dermatology

Background:

Granulomatous lobular mastitis (GM) is a rare, chronic, benign inflammatory breast disease.
It presents a diagnostic challenge, often mimicking inflammatory breast cancer.
GM causes significant morbidity in affected patients.

Observation:

GM typically presents as a large, painful breast lump with erythema.
Ulceration, abscess formation, and sinus tracts are common clinical signs.
A triple assessment is necessary for accurate diagnosis.

Findings:

GM is usually idiopathic and can persist for over 12 months.
Management options include conservative care, systemic corticosteroids (prednisone), methotrexate, or surgical excision.
No universally accepted management strategy exists; treatment is individualized.

Implications:

General practitioners require clinical updates on GM due to their primary role in patient assessment.
Patient support is essential for coping with the long-term nature of GM and chronic symptoms.
Further research may clarify optimal diagnostic and management pathways for GM.