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Related Concept Videos

Chronic Kidney Disease I: Introduction01:25

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Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
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Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
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Tuberculosis in Chronic Kidney Disease.

Mahesh Kumar Lal1, Satpal Singh2

  • 1Professor , Corresponding Author.

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Tuberculosis (TB) is more common in patients with chronic kidney disease (CKD). Screening CKD patients for TB is crucial due to overlapping symptoms and rising disease prevalence.

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Area of Science:

  • Nephrology
  • Infectious Diseases
  • Public Health

Background:

  • Chronic kidney disease (CKD) prevalence is rising globally, particularly in tuberculosis (TB) endemic regions like India.
  • The co-occurrence of CKD and TB poses significant public health challenges, especially in low- and middle-income countries.
  • Understanding the interplay between these two epidemics is critical for effective healthcare strategies.

Purpose of the Study:

  • To determine the prevalence of tuberculosis (TB) among patients diagnosed with chronic kidney disease (CKD).
  • To investigate the association between dialysis status and TB infection in CKD patients.

Main Methods:

  • A prospective study was conducted involving 160 CKD patients at Safdarjung Hospital, New Delhi.
  • Participants included patients with and without dialysis.
  • Comprehensive investigations were performed to detect any form of TB infection.

Main Results:

  • Tuberculosis was detected in 22 out of 160 CKD patients, representing a prevalence of 13.7%.
  • Extra-pulmonary TB (17 cases) was more common than pulmonary TB (5 cases).
  • TB infection was significantly more prevalent in patients undergoing dialysis (18 cases) compared to those not on dialysis (4 cases).

Conclusions:

  • Tuberculosis is notably more prevalent in individuals with chronic kidney disease.
  • CKD patients require vigilant screening for TB due to shared and overlapping clinical signs and symptoms.
  • Early detection and management of TB in CKD patients are essential for improved health outcomes.