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Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
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Adult Stem Cells01:33

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Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
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Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

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Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
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Stem Cell Culture01:17

Stem Cell Culture

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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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Tissue Renewal without Stem Cells01:23

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After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
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Embryonic Stem Cells00:57

Embryonic Stem Cells

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Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
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Rogue stem cell clinics.

Iain R Murray1, Jorge Chahla2, Rachel M Frank3

  • 1Department of Orthopaedic Surgery, University of Edinburgh, Edinburgh, UK.

The Bone & Joint Journal
|February 4, 2020
PubMed
Summary
This summary is machine-generated.

Concerns are rising regarding unproven stem cell therapies for musculoskeletal issues. This review addresses direct-to-consumer marketing, regulatory challenges, and recommends best practices for identifying illegitimate stem cell providers.

Keywords:
BiologicsDirect to consumer marketingRegulationStem Cells

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Area of Science:

  • Regenerative Medicine
  • Musculoskeletal Tissue Repair
  • Cell-Based Therapies

Background:

  • Cell therapies show promise for musculoskeletal tissue repair.
  • Growing concern exists regarding unverified clinical claims and risky procedures by some stem cell providers.
  • Many providers market 'stem cell' treatments without sufficient evidence of content or efficacy.

Purpose of the Study:

  • To outline the current landscape of stem cell-based treatments.
  • To analyze direct-to-consumer marketing strategies in this field.
  • To identify regulatory challenges and propose best practices for identifying illegitimate providers.

Main Methods:

  • Review of the current environment of stem cell treatments.
  • Analysis of direct-to-consumer marketing tactics.
  • Examination of regulatory hurdles and recommendations for best practices.

Main Results:

  • Identified widespread marketing of unproven stem cell therapies.
  • Highlighted difficulties in regulating clinics offering these treatments.
  • Outlined strategies for consumers to identify and report illegitimate providers.

Conclusions:

  • Urgent need for clear guidelines and regulation in the stem cell therapy market.
  • Consumers require education to discern legitimate treatments from unverified claims.
  • Recommendations provided for best practices and reporting of non-compliant providers.