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Updated: Dec 29, 2025

Intranasal Administration of CNS Therapeutics to Awake Mice
Published on: April 8, 2013
Just the facts: Hypertonic saline is just as good as (and probably better than) mannitol
1Dalhousie University, QEII Health Sciences Center, Departments of Emergency Medicine and Critical Care, Halifax, NS.
Abstract:
A 27-year-old female is brought to the emergency department (ED) by ambulance following a motor vehicle collision at highway speed. She was the belted driver. She has no significant past medical history and is on no medications. Following a prolonged extrication, she is intubated due to decreased level of consciousness before transport.
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