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Relationship Between Medication Literacy and Medication Adherence in Inpatients With Coronary Heart Disease in
Feng Zheng1, Siqing Ding2, Lin Lai1
1Department of Cardiology, The Third Xiangya Hospital of Central South University, Changsha, China.
Insights
Medication literacy is linked to better medication adherence in Chinese coronary heart disease patients. Improving medication literacy can enhance treatment adherence and patient outcomes.
Area of Science:
- Cardiology
- Health Literacy
- Public Health
Background:
- Medication adherence is crucial for managing coronary heart disease (CHD).
- Limited research exists on the relationship between medication literacy and adherence in CHD patients.
- Understanding this association is vital for improving patient outcomes.
Purpose of the Study:
- To assess medication literacy and adherence levels in Chinese inpatients with CHD.
- To investigate the association between medication literacy and medication adherence in this population.
Main Methods:
- Cross-sectional survey of 470 CHD inpatients in Changsha, China.
- Utilized the Morisky Medication Adherence Scale and the Chinese Version of the Medication Literacy Scale.
- Employed univariate analysis and binary logistic regression to identify predictors of adherence.
Main Results:
- Only 13.6% of patients demonstrated optimal medication adherence.
- 30.2% of patients had adequate medication literacy.
- Adequate medication literacy was an independent predictor of optimal medication adherence (OR 1.461).
Conclusions:
- A significant positive association exists between medication literacy and medication adherence in CHD patients.
- Medication literacy is a key factor for developing effective adherence interventions.
- Interventions targeting medication literacy may improve CHD management.
Abstract:
Background: Medication literacy may be associated with medication safety, and medication adherence is critical in treating coronary heart disease. Few studies have explored the association between medication literacy and medication adherence in patients with coronary heart disease. The aim was to investigate the status of medication literacy and medication adherence among Chinese inpatients with coronary heart disease, and explore the association between medication literacy and medication adherence. Methods: The study was a cross-sectional survey. Four hundred seventy inpatients with coronary heart disease were recruited from hospitals in Changsha, Hunan, China. Participants' demographic and clinical data were retrieved from hospital charts. Medication adherence was assessed using the four-item Morisky Medication Adherence Scale. Medication literacy was assessed using the Chinese Version of the Medication Literacy Scale. For univariate analysis, potential factors influencing medication adherence were tested by T-tests, analysis of variance, and the Kruskal-Wallis H test. Binary logistic regression model was conducted with medication adherence as the outcome variable in order to analyze the association between medication literacy and medication adherence in inpatients with coronary heart disease. Results: Among 512 participants, 470 (91.8%) produced valid responses for the survey. Mean (SD) of medication adherence score was 2.26 (13.6); only 13.6% had optimal medication adherence. Mean (SD) of medication literacy score was 7.52 (4.09); participants with adequate medication literacy was 30.2% (142). Binary logistic regression analysis indicated that medication literacy was an independent predictor associated with medication adherence. Participants with adequate medication literacy were more likely to have optimal medication adherence (OR 1.461 [95% CI: 0.114, 0.643]; P = 0.005), and participants with a high level of education (OR 0.613 [95% CI: 0.284, 0.694]; P< 0.001), a fewer number of medicines (OR 1.514 [95% CI: -0.631, -0.198]; P < 0.001), having medical insurance (OR 0.770 [95% CI: -1.769, 0.059]; P = 0.043), and single inpatients were more likely to be adherent (OR 1.655 [95% CI:-0.858, -0.149]; P = 0.005). Conclusions: The study indicates a significant association between medication literacy and medication adherence in patients with coronary heart disease. These results suggest that medication literacy is an important consideration in the development, implementation, and evaluation of medication adherence interventions.
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