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Related Experiment Videos

[An evaluation of predicting postoperative residual liver function using 99mTc tin colloid].

T Tamai1, I Hino, M Tanabe

  • 1Department of Radiology, Kagawa Medical School, Japan.

Radioisotopes
|October 1, 1988
PubMed
Summary

A new predictive index combining liver function and volume measurements can predict patient outcomes after liver resection. This index helps determine the safe limits for hepatic resection, improving patient safety.

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Area of Science:

  • Nuclear Medicine
  • Hepatology
  • Surgical Oncology

Background:

  • Liver function tests are crucial for assessing patients undergoing hepatic resection.
  • Technetium-99m tin colloid (99mTc) scintigraphy offers a method for evaluating liver function and volume.
  • Predicting residual liver function post-resection is vital for surgical planning.

Purpose of the Study:

  • To develop and validate a predictive index for residual liver function before hepatic resection.
  • To combine liver clearance rate (K value) and effective liver volume measurements.
  • To establish a threshold for safe hepatic resection based on the predictive index.

Main Methods:

  • Utilized 99mTc tin colloid scintigraphy to measure the K value and effective liver volume.

Related Experiment Videos

  • Calculated a predictive index by combining K value and effective liver volume.
  • Investigated the index in 24 patients with liver diseases prior to hepatic resection.

    • Main Results:

    • Three out of 24 patients died due to hepatic failure post-resection.
    • The predictive index was between 0.40-0.45 in two non-survivors and 0.338 in one.
    • Patients without hepatic failure generally had an index above 0.45 or between 0.40-0.45.

    Conclusions:

    • The predictive index effectively differentiates patients at risk of hepatic failure after resection.
    • A predictive index value between 0.40 and 0.45 appears to represent a critical threshold for hepatic resection.
    • This index aids in determining the limitations of hepatic resection to prevent post-operative complications.