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Malignant Thyroid-type Papillary Neoplasm in Struma Ovarii: A Case Report.
Syed Adeel Hassan1, Ali Akhtar2, Noor Ul Falah3
1Internal Medicine, Dow University of Health Sciences, Karachi, PAK.
Cureus
|February 4, 2020
Summary
Papillary thyroid carcinoma (PTC) within a struma ovarii (SO) is rare, presenting as an ovarian mass. This case highlights successful surgical management and a favorable prognosis for this uncommon gynecologic malignancy.
Area of Science:
- Gynecologic Oncology
- Endocrinology
- Pathology
Background:
- Papillary thyroid carcinoma (PTC) arising in a struma ovarii (SO) is an exceptionally rare gynecologic malignancy.
- SO is a teratoma containing thyroid tissue, and malignant transformation within it is infrequent.
- Clinical presentation often mimics common ovarian neoplasms, leading to diagnostic challenges.
Observation:
- A 51-year-old female presented with symptoms suggestive of an ovarian tumor, including a palpable mass and elevated CA-125.
- Abdominopelvic CT scan revealed findings consistent with a left ovarian tumor.
- The patient underwent extensive surgical debulking, including total abdominal hysterectomy and bilateral salpingo-oophorectomy.
Findings:
- Postoperative histopathological examination confirmed the diagnosis of papillary thyroid carcinoma within the struma ovarii, staged as IA.
- The patient did not require any adjuvant therapy following surgical resection.
- The patient remained disease-free for 24 months post-surgery with regular follow-up.
Implications:
- This case underscores the importance of considering rare diagnoses in gynecologic oncology.
- Complete surgical resection appears to be an effective primary treatment for early-stage PTC in SO.
- Further research is needed to establish definitive management guidelines for this rare condition.
