Multicentre study of prepectoral breast reconstruction using acellular dermal matrix.

Area of Science:

• Plastic Surgery
• Oncology
• Surgical Outcomes

Background:

• Single-stage breast reconstruction is common post-mastectomy.
• Prepectoral implant placement is an emerging technique.
• This study audits surgical outcomes of prepectoral reconstruction with acellular dermal matrix (ADM).

Purpose of the Study:

• To evaluate surgical outcomes of prepectoral breast reconstruction using ADM.
• To identify factors influencing complications and implant loss in this patient cohort.

Main Methods:

• A multicentre audit included 406 mastectomies with prepectoral reconstruction and ADM (Jan 2015-Dec 2017).
• Data collected included demographics, treatment details, and operative outcomes.
• Multivariable analysis examined factors affecting complications and implant loss.

Main Results:

• Median follow-up was 9.65 months, with a median hospital stay of 1 day.
• 90-day unplanned readmission was 15.7%, return-to-theatre rate was 16.7%.
• Major complications occurred in 15.3%, with a 90-day implant loss rate of 4.9%; no factors were significantly associated with outcomes.

Conclusions:

• Prepectoral breast reconstruction with ADM demonstrates satisfactory surgical outcomes.
• Extended follow-up is necessary to fully assess outcomes, particularly for patients receiving adjuvant radiotherapy.