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Related Concept Videos

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Inductively coupled plasma (ICP) is the common plasma source used in atomic emission spectroscopy (AES), a technique that detects and analyzes various elements in a sample. This method is often called inductively coupled plasma atomic emission spectroscopy (ICP-AES).
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Related Experiment Video

Updated: Dec 29, 2025

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A versatile and compact surface plasmon resonance spectrometer based on single board computer.

A Vestri1, G Margheri2, E Landini3

  • 1Molecular Biology Research Unit, Department of Experimental and Clinical Biomedical Sciences Mario Serio, University of Florence, Viale GB Morgagni 50, 50134 Firenze, Italy.

The Review of Scientific Instruments
|February 5, 2020
PubMed
Summary
This summary is machine-generated.

This study presents a compact, high-accuracy surface plasmon resonance (SPR) device built with low-cost hardware. The device achieves a refractive index resolution of 4.9 × 10-6 RIU, making lab-level research accessible.

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Area of Science:

  • * Physics and Chemistry
  • * Materials Science
  • * Optical Engineering

Background:

  • * Advancements in low-cost, high-performance hardware enable sophisticated scientific instrumentation.
  • * Surface Plasmon Resonance (SPR) is a powerful label-free technique for sensing applications.

Purpose of the Study:

  • * To demonstrate the hardware implementation of a compact Surface Plasmon Resonance (SPR) device.
  • * To achieve high accuracy and rapid measurement times suitable for diverse applications.
  • * To utilize readily available hardware for laboratory-level scientific equipment.

Main Methods:

  • * A Raspberry Pi single-board computer with a camera module for image acquisition.
  • * Python code for efficient data processing.
  • * A flexible optical setup with two configurations: inspection mode and angle-resolved measurement mode.

Main Results:

  • * Inspection mode precisely locates the interrogation beam, ensuring accurate sample analysis.
  • * Angle-resolved measurement mode enables real-time monitoring of reflectivity minimum with sub-pixel resolution.
  • * Achieved a bulk refractive index resolution of 4.9 × 10-6 refractive index units (RIU) with a 10-second acquisition time.

Conclusions:

  • * The developed compact SPR device offers high accuracy and efficiency using accessible hardware.
  • * The system's performance is suitable for various research and analytical applications.
  • * This implementation democratizes access to advanced SPR technology in research laboratories.