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Related Experiment Video

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Development of a Virtual Reality Assessment of Everyday Living Skills

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Published on: April 23, 2014

The Neuropsychiatric Inventory: Development and Applications.

Jeffrey Cummings^1,2

¹Department of Brain Health, School of integrated Health Sciences, UNLV, Las Vegas, NV, USA.

Journal of Geriatric Psychiatry and Neurology

|February 5, 2020

Summary

The Neuropsychiatric Inventory (NPI) is a validated tool for assessing behavioral symptoms in neurodegenerative disorders. It has been widely used in clinical trials and economic studies for over 25 years.

Keywords:

Alzheimer disease Neuropsychiatric Inventory (NPI)agitation apathy depression psychosis

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Area of Science:

Neuroscience
Psychiatry
Gerontology

Background:

The Neuropsychiatric Inventory (NPI) has been a cornerstone in studying neuropsychiatric symptoms for 25 years.
It is crucial for understanding behavioral changes in neurodegenerative conditions.

Purpose of the Study:

To review the historical development and application of the NPI.
To highlight its utility in research and clinical settings.

Main Methods:

The NPI uses a structured format with 10 (or 12) items, assessing frequency and severity.
It has demonstrated validity and reliability across numerous studies.
The instrument is available in approximately 40 languages with multiple versions for diverse clinical needs.

Main Results:

NPI studies reveal distinct behavioral symptom profiles across different neurological disorders.
The NPI has been instrumental in approximately 350 clinical trials.
It effectively quantifies the economic burden of behavioral symptoms in dementias.

Conclusions:

The NPI is an indispensable tool for evaluating behavioral changes in Alzheimer disease and other neurodegenerative disorders.
Its widespread use underscores its significance in clinical practice and research.