Minimizing risk of customized titanium mesh exposures - a retrospective analysis
Amely Hartmann1,2, Marcus Seiler3
1Private Practitioner, Affiliate to the Department of Oral and Maxillofacial Surgery, University Medical Centre of the Johannes Gutenberg University of Mainz, Augustusplatz 2, 55131, Mainz, Germany. amelyhartmann@web.de.
BMC Oral Health
|February 5, 2020
Summary
This study evaluated a new digital workflow for customized bone augmentation using titanium meshes. Autologous Platelet-Rich Fibrin (A®-PRF) significantly reduced mesh exposure, improving soft tissue healing in bone regeneration procedures.
Area of Science:
- Oral and Maxillofacial Surgery
- Regenerative Dentistry
- Digital Workflow in Dentistry
Background:
- Developing effective soft tissue management protocols is crucial for customized bone regeneration.
- This study aimed to assess a novel digital workflow protocol for customized bone augmentation.
Purpose of the Study:
- To evaluate a new digital protocol for customized bone augmentation.
- To investigate factors influencing soft tissue healing and implant success in bone regeneration.
Main Methods:
- A retrospective analysis of patients undergoing three-dimensional bone defect treatment using customized titanium mesh (Yxoss CBR®).
- Evaluation of defect characteristics, demographics, healing issues, and risk factors.
- Investigation of mesh exposure rates concerning surgical splint application, Autologous Platelet-Rich Fibrin (A®-PRF), and flap design.
Main Results:
- A total of 98 implants were placed, with Yxoss CBR® removed after an average of 6.53 months.
- Mesh exposure occurred in 25% of cases, with most being slight.
- Autologous Platelet-Rich Fibrin (A®-PRF) significantly reduced mesh exposure (p=0.029), while other factors like smoking, diabetes, and flap design did not significantly influence exposure rates. Female gender was associated with less exposure (p=0.043).
Conclusions:
- The digital protocol utilizing patient-specific titanium meshes, resorbable membranes, and bone grafting materials shows promise for bone augmentation.
- Autologous Platelet-Rich Fibrin (A®-PRF) is recommended to enhance soft tissue healing in these procedures.


