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Updated: Dec 29, 2025

Endoscopic Approach for Colloid Cyst Resection
Published on: May 23, 2025
[Effect of surgery of pulmonary cysts related to immunoglobulin light chain deposits]
P Delaey1, L Plawny2, A Nchimi3
1Département de médecine interne, cliniques universitaires Saint-Luc, université catholique de Louvain, Bruxelles, Belgique; Service de pneumologie, centre hospitalier de Luxembourg, Strassen, Luxembourg.
Introduction:
Light chain deposition disease is a rare anatomo-clinical disorder, which rarely leads to cystic lung destruction.
Case Report:
We report the case of a 62years old female patient with a history of a monoclonal gammopathy of unknown significance who developed progressive dyspnea. Thoracic CT-scan demonstrated a diffuse pulmonary cystic disorder with predominance in the right lower lobe. Thoracoscopic surgical resection of that lobe led to a diagnosis of non-amyloid kappa light chain deposits. Surgery also resulted in a lung volume reduction effect with clinical and functional benefits related to improved ventilation of adjacent segments.
Conclusion:
This report of pulmonary cystic disorder related to a light chain deposition disease highlights the potential clinical and functional benefits observed after lung volume reduction surgery.
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