Impact of concurrent right ventricular myocardial infarction on outcomes among patients with left ventricular

Related Experiment Video

Updated: Dec 29, 2025

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
14:35

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Published on: April 17, 2021

8.9K

Huocheng Liao1, Qiuyue Chen1, Lin Liu1

  • 1The Third People Hospital of Huizhou, The Affiliated Hospital of Guangzhou Medical University, Huizhou, Guangdong, China.

Scientific Reports
|February 5, 2020
PubMed

Insights

Right ventricular myocardial infarction (RVMI) in patients with left ventricular myocardial infarction (LVMI) is associated with worse outcomes. RVMI increases the risk of in-hospital mortality and acute heart failure, highlighting the importance of considering RV involvement in STEMI patients.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Clinical Research

Background:

  • Left ventricular myocardial infarction (LVMI) is a common form of heart attack.
  • The impact of concomitant right ventricular myocardial infarction (RVMI) on in-hospital outcomes for LVMI patients is not fully understood.

Purpose of the Study:

  • To compare in-hospital outcomes between patients with acute ST-segment elevation myocardial infarction (STEMI) involving the left ventricle (LVMI) with and without concurrent right ventricle (RVMI).

Main Methods:

  • A cohort of STEMI patients undergoing primary percutaneous coronary intervention (PCI) was divided into LVMI with and without RVMI groups.
  • In-hospital outcomes, demographic data, and clinical markers were compared between the two groups.

Main Results:

  • Patients with RVMI exhibited higher rates of diabetes, dyslipidemia, elevated C-reactive protein, B-type natriuretic peptide, and cardiac troponin-I.
  • RVMI was associated with lower left and right ventricular ejection fractions and higher mean pulmonary artery pressure.
  • Patients with RVMI had significantly higher odds of in-hospital all-cause mortality (4.1% vs 1.0%) and new-onset acute heart failure (3.4% vs 1.0%).
  • After adjustment, LVMI with RVMI remained independently associated with composite adverse outcomes (OR 1.66; 95% CI 1.39-2.04).

Conclusions:

  • Concomitant RVMI in patients with LVMI is associated with increased in-hospital complications, including higher mortality and acute heart failure.
  • Early recognition and management of RVMI in STEMI patients are crucial for improving patient outcomes.

More Related Videos

Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice10:18

Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice

Published on: February 1, 2022

3.4K
Myocardial Infarction and Functional Outcome Assessment in Pigs12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

28.5K

Related Concept Videos

Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
253
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
330
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
312
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
2.2K
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
287
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
222