Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA Bacteriophages01:26

DNA Bacteriophages

649
Bacteriophages, or phages, are viruses that specifically infect bacteria, utilizing their genetic material to hijack host cellular machinery for replication. DNA bacteriophages employ single-stranded DNA (ssDNA) or double-stranded DNA (dsDNA) genomes. These phages exhibit diverse replication strategies and host interactions, influencing their ecological roles and applications in biotechnology and medicine.ssDNA BacteriophagesssDNA phages, with their small genomes, utilize unique strategies to...
649
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

513
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
513
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

6.8K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
6.8K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

7.9K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
7.9K
Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

424
Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
424
Diversity of Archaea II01:24

Diversity of Archaea II

382
Archaea, one of the three domains of life, exhibit remarkable diversity and adaptability, thriving in both extreme and moderate environments. Historically, most identified archaea have been classified into two major phyla: Euryarchaeota and Crenarchaeota. However, recent molecular studies have expanded this classification to include three additional phyla: Thaumarchaeota, Nanoarchaeota, and Korarchaeota, each exhibiting unique characteristics and ecological roles.Thaumarchaeota: Mesophiles...
382

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Phage satellites induced by virulent phages are mobilized by natural competence leading to phage resistance in a new host.

Nature communications·2026
Same author

Phage host range: determinants, dynamics and applications.

Nature reviews. Microbiology·2026
Same author

Optimization of bacterial colonization in the gut of axenic and conventional zebrafish larvae using live food.

Microbiology spectrum·2026
Same author

An updated evolutionary classification of CRISPR-Cas systems including rare variants.

Nature microbiology·2025
Same author

Strengthening phage resistance of Streptococcus thermophilus by leveraging complementary defense systems.

Nature communications·2025
Same author

Complete genome of five <i>Acinetobacter baumannii</i> phages.

Microbiology resource announcements·2025

Related Experiment Video

Updated: Dec 29, 2025

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
09:40

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Published on: June 11, 2015

12.6K

Phage diversity, genomics and phylogeny.

Moïra B Dion1,2, Frank Oechslin1,2, Sylvain Moineau3,4,5

  • 1Département de biochimie, de microbiologie et de bio-informatique, Faculté des sciences et de génie, Université Laval, Québec City, Québec, Canada.

Nature Reviews. Microbiology
|February 5, 2020
PubMed
Summary
This summary is machine-generated.

Viral metagenomics reveals vast phage diversity across environments. Despite genomic novelty, structural proteins are conserved, driven by host-induced genetic exchange and mosaic genomes.

More Related Videos

Understanding the Impact of Temperate Bacteriophages on Their Lysogens Through Transcriptomics
09:23

Understanding the Impact of Temperate Bacteriophages on Their Lysogens Through Transcriptomics

Published on: January 5, 2024

2.4K
Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'
08:31

Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'

Published on: May 26, 2013

11.4K

Related Experiment Videos

Last Updated: Dec 29, 2025

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
09:40

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Published on: June 11, 2015

12.6K
Understanding the Impact of Temperate Bacteriophages on Their Lysogens Through Transcriptomics
09:23

Understanding the Impact of Temperate Bacteriophages on Their Lysogens Through Transcriptomics

Published on: January 5, 2024

2.4K
Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'
08:31

Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'

Published on: May 26, 2013

11.4K

Area of Science:

  • Microbiology
  • Virology
  • Bioinformatics

Background:

  • Viral metagenomics has accelerated the discovery of diverse bacteriophages (phages) in various ecosystems.
  • This expansion in knowledge highlights the vast, undiscovered viral world.
  • Despite genomic diversity, phage structural proteins exhibit significant conservation.

Purpose of the Study:

  • To review phage diversity at structural, genomic, and community levels.
  • To explore the evolutionary relationships shaping phage diversity.
  • To understand the role of genetic exchange and mosaic genomes in phage evolution.

Main Methods:

  • Review of recent literature on viral metagenomics.
  • Analysis of phage genomic and structural protein data.
  • Exploration of evolutionary dynamics and host-phage interactions.

Main Results:

  • Unprecedented catalogue of phages discovered across diverse environments.
  • Remarkable nucleotide sequence diversity contrasts with conserved structural proteins.
  • Phages exhibit complex evolutionary interconnections driven by host-imposed selective pressures.

Conclusions:

  • Phage diversity is shaped by a combination of genomic novelty and conserved structural elements.
  • Genetic exchange and mosaic genome structures are key drivers of phage evolution.
  • Understanding these dynamics is crucial for comprehending viral communities and their ecological roles.