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Updated: Dec 29, 2025
Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles
Published on: January 7, 2019
Flash nanoprecipitation of ultra-small semiconducting polymer dots with size tunability
Yuezhen He1, Xinyue Fan, Jian Sun
1Anhui Key Laboratory of Chemo-Biosensing and Ministry of Education Key Laboratory of Functional Molecular Solids, Laboratory of Biosensing and Bioimaging (LOBAB), College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, China. hyz2006@ahnu.edu.cn.
Abstract:
Small-sized semiconducting polymer dots (Pdots) provide better tissue and subcellular penetration while minimizing unspecific interactions, and make the fast clearance of Pdots from human bodies possible by urinary excretion. We employ a powerful and scalable technology, flash nanoprecipitation, to prepare Pdots with small sizes (hydrodynamic diameters ∼10 nm).
