Related Experiment Video
Updated: Dec 29, 2025

A Surgical Model of Heart Failure with Preserved Ejection Fraction in Tibetan Minipigs
Published on: February 18, 2022
[Diagnostics and treatment of chronic heart failure : Update 2020]
Gülmisal Güder1,2, Georg Ertl2, Christiane E Angermann3
1Medizinische Klinik und Poliklinik I, Kardiologie, Universität Würzburg, Würzburg, Deutschland.
Insights
Managing heart failure is complex due to aging populations and comorbidities. This review offers practical guidance for evidence-based treatment of chronic heart failure and its related conditions.
Area of Science:
- Cardiology
- Internal Medicine
- Geriatrics
Context:
- Heart failure (HF) is a systemic condition increasingly prevalent in aging global populations.
- Comorbidities significantly influence HF symptoms, progression, and patient prognosis.
- Recent advancements in pharmacotherapies and device-based treatments complicate HF management.
Purpose:
- To provide practical, evidence-based guidance for managing heart failure (HF).
- To address the complexities introduced by comorbidities in HF patients.
- To offer an up-to-date approach to HF treatment strategies.
Summary:
- This review synthesizes current evidence for managing chronic heart failure (HF).
- It emphasizes the critical role of comorbidities in HF and their impact on treatment.
- Novel pharmacotherapies and device-based options are discussed in the context of complex HF care.
Impact:
- Aims to simplify complex treatment decisions for clinicians managing heart failure (HF).
- Facilitates rational, guideline-adherent therapeutic choices for diverse HF patient populations.
- Supports improved patient outcomes through optimized, individualized HF management strategies.
Abstract:
Heart failure is a systemic disease. As populations are aging worldwide, the prevalence and importance of comorbidities as major determinants of heart failure symptoms, disease progression and prognosis are increasing. Since the last version of the European Society of Cardiology guidelines for the diagnosis and treatment of heart failure was published in 2016, promising novel pharmacotherapies for chronic heart failure and its comorbidities and new device-based treatment and monitoring options have become available; however, the broad range of therapeutic options as well as the diagnostic and therapeutic implications of comorbidities render the treatment of heart failure increasingly more complex. This review aims to provide practical guidance for a rational up-to-date approach to the evidence-based management of heart failure.
More Related Videos
Related Concept Videos
Heart Failure V: Medical Management
Heart Failure IV: Classification and Diagnostic Evaluation
Heart Failure VI: Adjunct Therapies
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy V: Interprofessional Care
Heart Failure VII: Nursing Interventions

