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First field trial of fox vaccination against rabies using a vaccinia-rabies recombinant virus
P P Pastoret1, B Brochier, B Languet
1Department of Virology-Immunology, Faculty of Veterinary Medicine, Brussels, Belgium.
Abstract:
A field trial of fox vaccination against rabies using a vaccinia-rabies recombinant virus was carried out in Belgium on October 24, 1987. Each vaccine capsule contained a suspension of 10(8) TCID50 of the recombinant virus and was introduced into a chicken head. Each chicken head contained 150 mg of tetracycline as a marker of uptake. Two hundred and fifty heads were distributed in an area of 6 km2 situated within a military zone. The bait uptake was monitored for 15 days after the distribution. Sixty-three per cent of the chicken heads were taken by wild animals within that period. The trial was controlled according to the rules defined by the World Health Organisation.