Cell Biology: Function Guides Form of Auditory Sensory Cells
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Updated: Dec 29, 2025

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Initiating Differentiation in Immortalized Multipotent Otic Progenitor Cells
Published on: January 2, 2016
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Jamis McGrath1, Benjamin J Perrin1
1Department of Biology, Indiana University-Purdue University Indianapolis, Indianapolis, IN 46202, USA.
Current Biology : CB
|February 5, 2020
Abstract:
Mechanosensory bundles on auditory sensory cells are composed of stereocilia that grow in rows of decreasing height. This pattern depends on the specification of the eventual tallest row, then the assignment of distinct molecular identities to the shorter rows. Mechanotransduction refines and maintains row identity, thus instructing the form of the bundle.
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