Related Experiment Video
Updated: Dec 29, 2025
11:14
Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
Published on: October 2, 2016
12.0K
Oleander and Datura Poisoning: An Update.
Vijay V Pillay1, Anu Sasidharan2
1Department of Forensic Medicine and Toxicology, Poison Control Centre, Amrita School of Medicine, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Summary
Oleander and Datura poisoning are significant health concerns in India. This review highlights current management and treatment strategies for toxicity from these common toxic plants.
Area of Science:
- Toxicology
- Ethnobotany
- Public Health
Background:
- India faces a high incidence of poisoning, with toxic plants contributing significantly.
- Oleander (Nerium oleander) and Datura species are ubiquitous and frequently implicated in poisoning cases across India.
- Poisoning can result from accidental exposure or intentional ingestion.
Purpose of the Study:
- To review management principles for Oleander and Datura poisoning.
- To survey literature on current treatment concepts for plant-induced toxicity.
Main Methods:
- Literature review and synthesis of existing data on Oleander and Datura toxicity.
- Analysis of management strategies and treatment protocols.
Main Results:
- Oleander and Datura are common toxic plants in India, causing frequent poisonings.
- Review covers principles of managing toxicity from these plants.
- Highlights current concepts in treating poisoning from Oleander and Datura.
Conclusions:
- Effective management and treatment protocols are crucial for Oleander and Datura poisoning.
- Understanding regional variations and commonalities in plant toxicity is important.
- Continued research and awareness are needed to address plant poisoning effectively.
Related Concept Videos
01:26Anticholinesterase Agents: Poisoning and Treatment
1.4K
Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
1.4K
01:14Prevention of Further Absorption of Poison
1.2K
In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
1.2K
01:17Antidotes
976
Antidotes are medicinal substances used to counteract the harmful effects of toxins or drugs in the body. They function in various ways, each uniquely designed to combat specific toxic compounds.
Specific antidotes operate by inhibiting the enzymes that control biochemical pathways, reducing the production of harmful metabolites.
An example of an antidote is atropine, which counteracts the detrimental effects of cholinesterase inhibitors. It achieves this by deactivating muscarinic receptors,...
Specific antidotes operate by inhibiting the enzymes that control biochemical pathways, reducing the production of harmful metabolites.
An example of an antidote is atropine, which counteracts the detrimental effects of cholinesterase inhibitors. It achieves this by deactivating muscarinic receptors,...
976
01:26Enhanced Elimination of Poison
797
Poison can be effectively removed from the gastrointestinal (GI) tract through various decontamination procedures.
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
797
01:36Types of Toxins
3.1K
Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
3.1K
01:26Toxic Reactions: Overview
1.7K
When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
1.7K