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Related Concept Videos

Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

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In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
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Corrosion02:49

Corrosion

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The degradation of metals due to natural electrochemical processes is known as corrosion. Rust formation on iron, tarnishing of silver, and the blue-green patina that develops on copper are examples of corrosion. Corrosion involves the oxidation of metals. Sometimes it is protective, such as the oxidation of copper or aluminum, wherein a protective layer of metal oxide or its derivatives forms on the surface, protecting the underlying metal from further oxidation. In other cases, corrosion is...
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Toxic Reactions: Overview01:26

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When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
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Esophageal Perforation-I: Introduction01:22

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Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
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Corrosion of Reinforcement01:27

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The corrosion of steel reinforcement within concrete is a process influenced by the material's inherent properties and external factors. The high pH level of around 13, provided by calcium hydroxide present in concrete, initially protects the steel reinforcement by promoting the formation of a passive iron oxide layer on its surface.
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Anticholinesterase Agents: Poisoning and Treatment01:26

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Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.     
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Related Experiment Video

Updated: Dec 29, 2025

Inducing Acute Liver Injury in Rats via Carbon Tetrachloride CCl4 Exposure Through an Orogastric Tube
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Corrosive Ingestion.

Raja Kalayarasan1, Nilakantan Ananthakrishnan2, Vikram Kate3

  • 1Department of Surgical Gastroenterology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Indian Journal of Critical Care Medicine : Peer-Reviewed, Official Publication of Indian Society of Critical Care Medicine
|February 6, 2020
PubMed
Summary

Corrosive ingestion is a significant health issue in India, often resulting from inadequate caustic substance regulation. This review details its epidemiology, management, and long-term consequences.

Keywords:
Caustic injuryCorrosiveEsophageal strictureGastric stricturePoisoning

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Area of Science:

  • Gastroenterology
  • Toxicology
  • Public Health

Background:

  • Corrosive ingestion is a prevalent issue in developing nations, particularly India, linked to lax regulations on caustic substance sales.
  • Inadequate management of acute corrosive injuries is common due to limited physician experience, leading to significant tissue damage.

Purpose of the Study:

  • To review the epidemiology and pathophysiology of corrosive ingestion.
  • To outline principles for managing acute corrosive injuries.
  • To discuss long-term effects and prevention strategies for caustic ingestion.

Main Methods:

  • Literature review focusing on corrosive ingestion.
  • Synthesis of data on epidemiology, pathophysiology, acute management, long-term sequelae, and prevention.

Main Results:

  • Corrosive ingestion causes significant morbidity, especially in regions with poor regulatory control.
  • Effective acute management is crucial to minimize tissue damage and prevent long-term complications.
  • Delayed or improper care exacerbates injury severity and increases the risk of adverse outcomes.

Conclusions:

  • Strict regulation of caustic substance sales is essential for prevention.
  • Standardized protocols and physician education are vital for improving acute corrosive injury management.
  • Addressing both immediate and long-term aspects of corrosive ingestion is critical for patient outcomes.