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Published on: September 9, 2020
Survival of osteosarcoma patients following diagnosis of synchronous skip metastases
Peiming Yang1, Magdalena Gilg1, Scott Evans1
1Royal Orthopaedic Hospital NHS Foundation Trust, UK.
Background:
We aim to investigate the prognostic implications of synchronous skip metastases in osteosarcoma by presenting the largest single centre series to date.
Methods:
Retrospective study of 21 osteosarcoma patients with skip metastases treated between 1983 and 2004.
Results:
No statistical difference in overall survival was demonstrated when comparing presence of lung metastases to those without (p = 0.859). No statistical difference was found in overall survival according to age group (<18yrs vs >18yrs; p = 0.126), or to percentage chemotherapy-induced bone necrosis (<90% vs >90%; p = 0.056).
Conclusions:
The presence of skip metastases confers a very poor prognosis as an independent variable.
Level Of Evidence:
III.
