Related Experiment Video
Updated: Dec 29, 2025
03:10
Author Spotlight: Development and Evaluation of a Compound Acne Rodent Model Using C. acnes and Oleic Acid
Published on: November 1, 2024
3.5K
Correlation Between Lipid Profile and Acne Vulgaris
Mohammadreza Sobhan1, Mohammad Ali Seif Rabiei2, Maryam Amerifar1
1Psoriasis Research Center, Department of Dermatology, Sina Hospital, Hamadan University of Medical Sciences, Hamadan, Iran.
Clinical, Cosmetic and Investigational Dermatology
|February 6, 2020
Summary
Acne patients often exhibit abnormal lipid profiles, with elevated cholesterol levels being the most common finding, especially in men. This suggests that monitoring lipid profiles may be beneficial for individuals with acne vulgaris.
Area of Science:
- Dermatology
- Clinical Biochemistry
Background:
- Acne vulgaris is a prevalent skin condition influenced by multiple pathogenic factors.
- Understanding metabolic alterations in acne patients is crucial for comprehensive management.
Purpose of the Study:
- To investigate potential lipid profile abnormalities in patients diagnosed with acne vulgaris.
- To compare lipid parameters between acne patients and healthy controls.
Main Methods:
- A descriptive, analytical, cross-sectional study design was employed.
- 45 acne vulgaris patients and 45 matched healthy controls were recruited.
- Plasma levels of total cholesterol, LDL, HDL, and triglycerides were measured.
Main Results:
- Acne patients demonstrated significantly higher total cholesterol levels compared to controls (P=0.025).
- Elevated cholesterol was particularly pronounced in male acne patients (P=0.04).
- While other lipids (TG, LDL, HDL) were higher in patients, these differences were not statistically significant.
Conclusions:
- Lipid profile alterations are observed in acne vulgaris patients, with hypercholesterolemia being a frequent derangement.
- The findings highlight a potential link between acne and cholesterol metabolism, especially in males.
- Routine lipid profile screening may be a valuable adjunct in the clinical management of acne.
Related Concept Videos
01:29Cholesterol: Significance and Regulation
1.2K
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Considering cholesterol and...
1.2K
01:25Blood Studies for Cardiovascular System III: Serum Lipid Profile
515
Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
515
01:24Lipid Absorption
2.3K
Dietary triglycerides from chyme in the duodenum are mixed with bile salts produced by the liver to emulsify fats. As a result, large droplets are broken down into smaller ones, increasing the surface area for enzymatic action. Once emulsified, pancreatic lipases hydrolyze the triglycerides into free fatty acids and monoglycerides.
These breakdown products bind with bile salts and lecithin to form micelles, which quickly pass between microvilli to come in close contact with the apical...
These breakdown products bind with bile salts and lecithin to form micelles, which quickly pass between microvilli to come in close contact with the apical...
2.3K
01:24Overview of Lipid Metabolism
4.6K
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
4.6K
01:31Lipid-derived Compounds in the Human Body
6.1K
Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
6.1K
01:06Lipid Digestion
98.3K
Lipids are large molecules that are generally not water-soluble. Since most of the digestive enzymes in the human body are water-based, there are specific steps the body must take to break down lipids and make them available for use.
98.3K