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Updated: Dec 29, 2025
A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis
Published on: April 10, 2019
A Rare Case Report of Acute Necrotizing Encephalopathy of Childhood
Seyed Ahmad Hosseini1, Fatemeh Sadat Tabatabaei1, Mohammad Hadi Molseghi2
1Children's and Neonatal Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Objective:
Acute necrotizing encephalopathy of childhood (ANEC) is a fast growing disease, accompanied by progressive encephalopathy. The aim of this study was to report a rare case of ANEC in a four-year-old boy with bilateral thalamic necrosis and non-fatal outcomes.
Case Report:
The patient was a four-year-old Iranian boy, without any history of health problems or hospitalization, except for jaundice and phototherapy in the neonatal period. He had no neurological signs or symptoms during admission, and he was admitted only with chief complaints of acute onset of fever, coryza, and icterus. In the neurological consultation, brain MRI was requested to analyze the possibility of brain damage. The results indicated the involvement of cerebellum, thalamus, and basal ganglia, which led to the diagnosis of ANEC.
Conclusion:
Based on our findings, although ANEC is a rare disease, it should not be underestimated.
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