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Published on: July 18, 2014
Prenatal diagnosis of congenitally corrected transposition of the great arteries
Nathalie Jeanne Bravo-Valenzuela1, Alberto Borges Peixoto1, Edward Araujo Júnior1
1Department of Obstetrics, Paulista School of Medicine - Federal University of São Paulo (EPM-UNIFESP), São Paulo-SP, Brazil.
Insights
Congenital heart disease, corrected transposition of the great arteries (cTGA), can be challenging to diagnose prenatally. This case highlights key indicators for identifying isolated cTGA in utero.
Area of Science:
- Cardiology
- Medical Imaging
- Pediatric Health
Background:
- Congenital heart disease (CHD) encompasses a range of conditions affecting heart structure.
- Congenitally corrected transposition of the great arteries (cTGA) is a rare CHD characterized by atrioventricular and ventriculoarterial discordance.
- cTGA often presents with other cardiac anomalies, complicating diagnosis.
Observation:
- Isolated cTGA, without additional cardiac malformations, may evade detection via standard obstetric cardiac ultrasound.
- Prenatal diagnosis of cTGA is crucial for timely intervention and improved outcomes.
- This manuscript details a case of isolated cTGA successfully diagnosed in utero.
Findings:
- Specific echocardiographic clues can aid in the prenatal identification of isolated cTGA.
- Recognizing these subtle findings is critical for accurate diagnosis.
- The case underscores the importance of detailed fetal cardiac assessment.
Implications:
- Improved prenatal diagnosis of cTGA can lead to better management strategies.
- Early detection facilitates appropriate planning for neonatal care and potential surgical interventions.
- Enhanced awareness of diagnostic clues can improve fetal cardiac screening protocols.
Abstract:
Congenitally corrected transposition of the great arteries is a rare and complex congenital heart disease. It essentially occurs with atrioventricular and ventriculoarterial discordance, in which the great vessels become parallel. Cases of corrected transposition of the great arteries are more frequently associated with other cardiac anomalies. In the fetus, corrected transposition of the great arteries may not be diagnosed on obstetric cardiac ultrasound, especially in the absence of other cardiac malformations (isolated corrected transposition of the great arteries). In this manuscript, we describe a case of isolated corrected transposition of the great arteries diagnosed in utero, and highlight the clues to make this diagnosis.
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