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Contrast-Enhanced Ultrasound Appearance of Hypervirulent Klebsiella pneumoniae Liver Abscesses

Gilbert Whang1, Robert D Harris1, Hisham Tchelepi1

  • 1Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
|February 6, 2020
PubMed

Insights

Hypervirulent Klebsiella pneumoniae causes community-acquired liver abscesses. Contrast-enhanced ultrasound (CEUS) effectively visualizes these abscesses, offering a radiation-free alternative to CT scans for diagnosis.

Area of Science:

  • Microbiology
  • Radiology
  • Hepatology

Background:

  • Klebsiella pneumoniae (KP) is increasingly recognized as a primary cause of pyogenic liver abscesses, particularly hypervirulent strains in immunocompetent individuals.
  • Community-acquired liver abscesses linked to KP are associated with distant septic seeding, especially in diabetic patients.
  • Previous studies have detailed contrast-enhanced computed tomography (CECT) findings for KP liver abscesses.

Observation:

  • Grayscale ultrasound (US) exhibits variable and often inconclusive features for diagnosing KP liver abscesses.
  • This study describes the specific features of KP liver abscesses visualized using contrast-enhanced ultrasound (CEUS).

Findings:

  • CEUS findings for KP liver abscesses demonstrated a strong correlation with established CECT findings.
  • CEUS provides detailed imaging of KP liver abscesses, mirroring CECT observations.

Implications:

  • Contrast-enhanced ultrasound (CEUS) offers a valuable, radiation-free imaging modality for diagnosing Klebsiella pneumoniae liver abscesses.
  • CEUS can replace or supplement CT scans, reducing patient exposure to ionizing radiation.
  • Improved diagnostic accuracy for KP liver abscesses using CEUS can lead to timely and appropriate patient management.
Keywords:
Klebsiella pneumoniaeabscesscontrastliverultrasound

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