Jove
Visualize
Contact Us

Related Concept Videos

Standard Precaution01:26

Standard Precaution

2.7K
Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
2.7K
Personal Protective Equipment01:20

Personal Protective Equipment

2.1K
Personal protective equipment (PPE) is unique clothing or equipment worn by an employee to minimize or prevent exposure to infectious agents. PPE creates a barrier between the employee and the infectious materials. PPE must be readily available in the patient care area. PPE includes gloves, gowns and aprons, masks and respirators, goggles, face shields, shoes, and headcovers:
2.1K
PPE Use in Healthcare Settings I: Donning01:22

PPE Use in Healthcare Settings I: Donning

1.5K
Donning PPE must be completed before contact with the patient. This process protects from infectious agents. The sequence and action included in each donning are critical, and the steps must be systematic to avoid exposure to pathogens. The institutional policy also needs to be followed while donning PPE. The pre-donning preparations are gathering equipment, inspecting the PPE equipment for tears, holes, or damage, removing jewelry, removing any garments below the elbows, and tying the hair...
1.5K
PPE Use in Healthcare Settings II: Doffing01:10

PPE Use in Healthcare Settings II: Doffing

1.5K
The sequence of removing or doffing PPE starts with the gloves, as they are the most contaminated. Next is removal of the face shield or goggles, as they would interfere with removing other PPE. Then remove the gown, followed by the mask or respirator. Perform hand hygiene between steps if hands become contaminated and immediately after removing all PPE. Generally, the outside front and sleeves of the isolation gown, the goggles or the mask, the respirator, and the face shield are contaminated.
1.5K
Cleaning, Sterilization, and Disinfection01:30

Cleaning, Sterilization, and Disinfection

9.5K
Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
9.5K
Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

1.8K
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Homeopathy? Absurd.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists·1996
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Dec 29, 2025

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 1. Biosafety Level 4 Suit Laboratory Suite Entry and Exit Procedures
09:54

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 1. Biosafety Level 4 Suit Laboratory Suite Entry and Exit Procedures

Published on: October 3, 2016

36.8K

Quality Control: Personal Protective Equipment for Use When Handling Hazardous Drugs.

L R Dillon1

  • 1Independent consultant and surveyor, Loveland, Colorado. lrdillon123@gmail.com.

International Journal of Pharmaceutical Compounding
|February 6, 2020
PubMed
Summary

United States Pharmacopeia Chapter 800 requires healthcare facilities to maintain a hazardous drug list. This guide details personal protective equipment (PPE) for safe handling, from receipt to disposal, including compounding.

More Related Videos

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 3. Aerobiology
11:13

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 3. Aerobiology

Published on: October 3, 2016

15.0K
Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 4. Medical Imaging Procedures
09:36

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 4. Medical Imaging Procedures

Published on: October 3, 2016

11.4K

Related Experiment Videos

Last Updated: Dec 29, 2025

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 1. Biosafety Level 4 Suit Laboratory Suite Entry and Exit Procedures
09:54

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 1. Biosafety Level 4 Suit Laboratory Suite Entry and Exit Procedures

Published on: October 3, 2016

36.8K
Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 3. Aerobiology
11:13

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 3. Aerobiology

Published on: October 3, 2016

15.0K
Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 4. Medical Imaging Procedures
09:36

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 4. Medical Imaging Procedures

Published on: October 3, 2016

11.4K

Area of Science:

  • Pharmaceutical Sciences
  • Occupational Health and Safety

Background:

  • United States Pharmacopeia (USP) Chapter 800 mandates hazardous drug (HD) management in healthcare.
  • Facilities must maintain a comprehensive HD list, including NIOSH-designated drugs and other substances of concern.
  • Safe handling protocols are crucial to minimize exposure risks for healthcare personnel.

Purpose of the Study:

  • To provide detailed guidance on personal protective equipment (PPE) for handling hazardous drugs.
  • To outline best practices for donning, using, and doffing PPE during all stages of HD management.
  • To ensure compliance with USP Chapter 800 requirements for hazardous drug handling.

Main Methods:

  • Review of USP Chapter 800 guidelines and NIOSH hazardous drug lists.
  • Identification of essential personal protective equipment (PPE) for hazardous drug handling.
  • Development of step-by-step protocols for PPE donning and doffing.
  • Integration of PPE guidance into the complete hazardous drug handling workflow.

Main Results:

  • Specific recommendations for appropriate PPE, including gloves, gowns, respiratory protection, and eye/face protection.
  • Clear instructions on the sequence and location for donning and doffing PPE.
  • Comprehensive coverage of PPE use in both sterile and nonsterile compounding environments.
  • Guidance applicable from drug receipt through final disposal.

Conclusions:

  • Adherence to USP Chapter 800 guidelines, including proper PPE use, is essential for safe hazardous drug handling.
  • Standardized protocols for PPE management mitigate risks associated with hazardous drug exposure.
  • This guidance supports healthcare entities in establishing robust hazardous drug safety programs.