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Melanotic Neuroectodermal Tumor of Infancy: A Rare Case Report
1Department of Pathology, Mahatma Gandhi Medical College & Hospital, Jaipur, IND.
Cureus
|February 7, 2020
Summary
Melanotic neuroectodermal tumor of infancy (MNTI), a rare neural crest tumor, typically affects the infant maxilla. This case details a successful wide local excision and histopathological confirmation of MNTI in a three-month-old female.
Area of Science:
- Pediatric Oncology
- Oral Pathology
- Developmental Biology
Background:
- Melanotic neuroectodermal tumor of infancy (MNTI) is a rare, benign neoplasm of neural crest origin.
- MNTI predominantly affects the maxilla in infants under one year old.
- Early diagnosis and treatment are crucial for favorable outcomes.
Observation:
- A three-month-old female infant presented with a rapidly growing intraoral swelling.
- Radiological imaging identified a tumor in the right maxilla.
- The lesion was surgically removed via wide local excision.
Findings:
- Histopathological examination revealed a biphasic cell population characteristic of MNTI.
- Melanin pigment deposition was noted within the tumor cells.
- Immunohistochemistry confirmed the diagnosis of melanotic neuroectodermal tumor of infancy.
Implications:
- This case highlights the importance of prompt diagnosis and surgical management of MNTI.
- Accurate histopathological and immunohistochemical analysis are essential for definitive diagnosis.
- Understanding MNTI's presentation aids in early detection and intervention in pediatric patients.
