Related Experiment Video
Updated: Dec 29, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
Published on: June 6, 2025
[Research Advance on Classic Wnt Pathway in Chronic Myelogenous Leukemia--Review]
Zhen-Rui Cao1, Xiao-Peng Chen1, Jing Hu2
1Chongqing Medical University;Chongqing 400016, China.
Abstract:
Abstract Chronic myelogenous leukemia (CML) is a hematological malignancy that seriously threatens the lives of patients. It was found that there are abnormal classic Wnt pathway, that is, Wnt/β-catenin signaling pathways in CML cells, moreover, Wnt/β-catenin signaling pathway is involved in the growth and proliferation of CML cells, and closely relates with the self-renewal ability of CML leukemic stem cells. This review summarizes the recent studies on the relationship between Wnt/β-catenin signaling pathway and CML, and the researches on the targeting inhibition of Wnt/β-catenin signaling pathway in CML treatment, thus to provide new ideas for the treatment of CML.
Related Concept Videos
Canonical Wnt Signaling Pathway
Non-Canonical Wnt Signaling Pathways
Differentiation of Common Myeloid Progenitor Cells
Abnormal Proliferation

