Related Experiment Video
Updated: Dec 29, 2025
09:26
Synthesis and Characterization of Supramolecular Colloids
Published on: April 22, 2016
10.3K
Colloidal Transformations in MS2 Virus Particles: Driven by pH, Influenced by Natural Organic Matter
Samuel Watts1, Timothy R Julian2,3,4, Katharina Maniura-Weber1
1Biointerfaces Lab , Empa, Swiss Federal Laboratories for Material Science and Technology , Lerchenfeldstrasse 5 , 9014 St. Gallen , Switzerland.
ACS Nano
|February 7, 2020
Summary
Water pH and natural organic matter significantly impact virus structure and aggregation, crucial for improving drinking water filtration and removal of enteric viruses like norovirus and rotavirus.
Area of Science:
- Environmental Science
- Water Treatment
- Nanotechnology
Background:
- Enteric viruses in water cause disease outbreaks.
- Viruses' nanoscale size challenges removal by conventional filtration.
- Understanding virus-host interactions is key to effective water purification.
Purpose of the Study:
- Investigate the colloidal nanostructure of MS2 bacteriophage.
- Determine the influence of pH and natural organic matter on virus structure.
- Inform the design of advanced virus removal technologies.
Main Methods:
- Utilized dynamic light scattering, small-angle X-ray scattering, and cryogenic transmission electron microscopy.
- Examined MS2 bacteriophage behavior across a range of pH values.
- Assessed the impact of simulated natural organic matter on virus aggregation.
Main Results:
- Water pH critically affects MS2 bacteriophage structure, with spherical 27 nm particles at pH 7.0-9.0 and micrometer aggregates at pH 3.0.
- Natural organic matter promotes repulsion between virus particles and aids disaggregation.
- Observed reversible structural transformations in MS2 bacteriophage based on pH.
Conclusions:
- pH and natural organic matter are key factors in virus behavior in aquatic environments.
- Findings enhance understanding of virus interactions for improved water treatment strategies.
- Results guide the development of novel filtration materials for effective virus removal.
More Related Videos
10:18Making Conjugation-induced Fluorescent PEGylated Virus-like Particles by Dibromomaleimide-disulfide Chemistry
Published on: May 27, 2018
7.3K
08:14Analysis of the Solvent Accessibility of Cysteine Residues on Maize rayado fino virus Virus-like Particles Produced in Nicotiana benthamiana Plants and Cross-linking of Peptides to VLPs
Published on: February 14, 2013
11.4K
Related Concept Videos
01:09Colloidal precipitates
4.6K
The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
4.6K
03:22Colloids
20.4K
Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles that are visible to the naked eye or can be seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. On the other hand, a solution is a homogeneous mixture in which no settling occurs and in which the dissolved...
20.4K
01:06Coagulation
1.1K
Colloidal solids are solid particles suspended in solution. They are usually negatively charged, attracting a compact primary layer of positively charged ions, which attract more counterions to form an electrical double layer. Electrostatic repulsion between the charged double layers prevents the particles from colliding, stabilizing the colloids. These solids are often undesirable because they can contain toxins that are difficult to remove. Coagulation is a technique that helps aggregate and...
1.1K
01:26Transformation
591
Microbial communities are dynamic environments where cell lysis releases free DNA into the surroundings. Other cells can take up this extracellular DNA through a process known as transformation.When a cell incorporates this foreign DNA into its genome, resulting in genetic modification, the process is known as transformation. Cells capable of this process are termed competent. Competence can be natural, as observed in certain bacteria and archaea, or artificially induced in the...
591
01:26DNA Bacteriophages
649
Bacteriophages, or phages, are viruses that specifically infect bacteria, utilizing their genetic material to hijack host cellular machinery for replication. DNA bacteriophages employ single-stranded DNA (ssDNA) or double-stranded DNA (dsDNA) genomes. These phages exhibit diverse replication strategies and host interactions, influencing their ecological roles and applications in biotechnology and medicine.ssDNA BacteriophagesssDNA phages, with their small genomes, utilize unique strategies to...
649
01:17Colloids and Suspensions
2.9K
Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles visible to the naked eye or seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. The suspended particles in a suspension settle out after some time of mixing. The separation of particles from a suspension is...
2.9K