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Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
Published on: August 30, 2020
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Depression after Subarachnoid Hemorrhage: A Systematic Review
Wai Kwong Tang1, Lisha Wang1, George Kwok Chu Wong2
1Department of Psychiatry, Chinese University of Hong Kong, Hong Kong, China.
Journal of Stroke
|February 7, 2020
Summary
Depression is a frequent and persistent complication following subarachnoid hemorrhage (SAH), impacting patient quality of life. Further research is needed to understand its development and effective treatments.
Area of Science:
- Neurology
- Psychiatry
- Public Health
Background:
- Depression frequently complicates neurological disorders, including non-traumatic subarachnoid hemorrhage (SAH).
- Understanding post-SAH depression is crucial due to its debilitating nature and impact on recovery.
Purpose of the Study:
- To systematically review studies on the frequency, severity, and time course of depression after SAH.
- To identify factors associated with post-SAH depression and its impact on quality of life.
Main Methods:
- A systematic search of the PubMed database was conducted.
- Studies included were published in English, involved patients over 18 years old, and had at least 40 participants diagnosed with depression post-SAH.
Main Results:
- 55 studies involving 6,327 patients were analyzed.
- The weighted proportion of depression after SAH was 28.1%, persisting long-term.
- Associated factors included female sex, prior depression, anxiety, substance use, cognitive impairment, fatigue, and physical disability.
Conclusions:
- Depression is a common and persistent condition following SAH.
- Further research is required to elucidate the neurobiological underpinnings and temporal patterns of post-SAH depression.
- Randomized controlled trials for treating SAH-related depression are necessary.
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